PDT photodynamic therapy Tutorial : acne treatment with Omega LED light

by admin // 2018年7月16日 // No Comments

What is PDT photodynamic therapy acne treatment?

PDT photodynamic acne therapy by using a non-side-effect photosensitizer that works with Omega LED light source to treat acne. It is called PDT photodynamic therapy. PDT GEL is a new concept of PDT acne treatment compared to traditional ALA-based photosensitizers, which use the skin protein component tryptophan to kill bacteria and release by-product amino acids. No burns, no pain, no tanning, no side effects! Now you can experience PDT photodynamic therapy for effective treatment of acne. In addition to the face, PDT gel can also be used on the back or anywhere on your body. Without the need for cumbersome application with MTS electric micro-needle, you don’t need to reconcile the product to consume a lot of time. All you have to do is to apply PDT gel on the skin of the patient along with the LED light source. You can treat your patient’s face or body, as long as there is acne problem. The treatment time is faster and more convenient!

PDT gel photodynamic therapy: Buy PDT GEL photosensitizer at gangnam style-shop.com!

Photodynamic therapy (PDT), sometimes called photochemotherapy, is a light therapy involving light and photosensitizers. PDT has been proven to kill microbial cells, including bacteria, fungi and viruses. PDT skin is widely used to treat acne problems. This treatment is especially useful in cases of severe acne that do not respond to other treatments. PDT acne treatment also has effects on other skin conditions such as sunburned skin, precancerous cells and skin infections. PDT Photodynamic Therapy also reduces the size and activity of oil-producing glands on the skin, called the sebaceous glands. Excessive activity and inflammation of these glands can cause more severe acne. PDT photodynamic therapy is often more effective for inflammatory acne than non-inflammatory acne.

What is PDT photodynamic therapy acne treatment?

Pdt photodynamic therapy acne treatment for back

New concept PDT GEL riboflavin and tryptophan treatment principle

Photosensitizer is very important in PDT photodynamic therapy

1. Riboflavin activates tryptophan after exposure to blue light to form active free radicals.

2. Active radicals react with water molecules to produce ROS

3. ROS has the effect of reducing the secretion of acne bacteria and sebum

4. After the influence of tryptophan, by-products rapidly decompose as amino acids are discharged through metabolic pathways in the skin.

5. It does not cause any side effects, no need to worry about redness, burning or tanning

Why not use chlorophyll ALA aminolevulinic acid component of photosensitizer?

5-Aminolevulinic acid (ALA), an endogenous biochemical substance produced by ALA dehydratase and a series of enzymatic actions to produce protoporphyrin IX (PPIX) with strong photosensitivity. The synthesis speed of PPIX depends on the picking speed of this product, and this product is regulated by the feedback of free hemoglobin concentration. The exogenous product can bypass the feedback inhibition system and make the cells synthesize a sufficient amount of PPIX. The acne containing PPIX is irradiated with 420-640 nm light, and singlet oxygen (-O2) is generated during energy transfer. When the oxygen reaches a certain concentration, cell death (phototoxicity) can be induced.

Side effects: When treated with ALA, there is no selective destruction of normal tissues around it, such as oxidized proteins, liposomes and other subcutaneous cell structures. Oxygen free radicals generated under the pathological conditions of this product overload will lead to Acute periodic porphyria. In addition, this product will cause the release of iron ions in ferritin. Which will aggravate the oxidation of cells, it will lead to acute periodic porphyria. Some people will have erythema and swelling. ALA aminolevulinic acid also causes pigmentation, which is an anti-black phenomenon in some people during the treatment.

Differences between photosensitizers for PDT photodynamic therapy

PDT photosensitizer for PDT photodynamic therapy

Treatment application process

1. Clean and disinfect skin before doing PDT photodynamic therapy

2. Squeeze the acne on your face (use a needle to gently puncture the area of the acne and squeeze out the pus)

3. Remove the cover of PDT Gel and replace it with a closed conical cover

4. Apply PDT Gel to your face, avoiding applying near the lips and around your eyes

5. Cover the face with plastic wrap, leave the lips and eyes area

6. Put the towel on your face for 20 minutes to block the light source to allow the product to fully penetrate. If you operate in a lighted room, you need to turn off the light.

7. Turn on the 415nm, 635nm pulsed LED light, each pulse for 10 minutes

8. Complete treatment, clean the skin

9. Place the Glamour Bio Cellulose Repair Mask for 20 minutes to clam your skin.

10. Always apply sunscreen after treatment, you need to apply sunscreen during the whole treatment period.

PDT photodynamic acne therapy usually takes 3 to 5 sessions for a complete treatment, depending on the skin condition of each patient. Each treatment interval is one week, but can be adjusted according to the patient’s skin condition. You can perform other skin treatment when doing PDT photodynamic therapy.

PDT photodynamic therapy before & after pictures

PDT photodynamic therapy acne treatment review

Important things to know after procedure

1. You can wash your face or having light makeup on the same day after treatment.

2. Please be gently cleaning your face to avoid irritating the skin.

3. Please try to avoid UV rays during the whole PDT photodynamic acne treatment always remember to apply sunscreen.

4. Please do not go to sauna, or having heavry exercise, etc. for 2-3 days after use.

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Hyaldew希雅德长效玻尿酸微珠铰链技术

by admin // 2018年7月15日 // No Comments

Hyaldew希雅德长效玻尿酸

HyalDew希雅德玻尿酸在韩国制造，是唯一一款获得CE认证的韩国玻尿酸，韩国KFDA和GMP认证，安全与质量的保证。希雅德独有微珠铰链专利技术，可以说是韩国玻尿酸在世界上最具影响力的品牌，畅销美国，欧洲，南美和中东等地。也是韩国玻尿酸进入铰链时代的领军产品。HyalDew采用100%透明质酸成分，无任何其他添加，利用HA多重分级微珠铰链技术达到玻尿酸的超长效、持久定性的效果。

Hyaldew希雅德玻尿酸的专利微珠铰链技术

对于玻尿酸本身来说，铰链技术是整个玻尿酸发展史中最重要的一步，带铰链的玻尿酸维持时间久，不带教练的玻尿酸属于关节润滑剂，例如海珠水光针，东国水光针等产品。希雅德的微珠铰链专利技术则是玻尿酸自然铰链技术的又一重大技术上的突破。那么人工铰链和自然铰链有什么区别呢？

相比之下，人工铰链有较多的杂质，自然铰链的玻尿酸经过自体的吸收，不会残留下任何的异物，会随着人体本身的新陈代谢进行吸收以及分解，对身体不会造成任何的伤害和负担，而人工的铰链，则会在体内造成大量的垃圾残留。

HyalDew希雅德在保持最自然铰链的同时，以先进稳定的专利微珠铰链技术保证了玻尿酸的持久性，不仅维持了玻尿酸的100%纯天然特质又解决了玻尿酸维持时间短在吸收过程中容易变形的缺点。

HyalDew希雅德在首尔大学医院完成了出口许可，并通过日本严格的5年临床试验，是最为安全有效的一款玻尿酸产品。

专利技术介绍：

1.希雅德的三段分解与结合工序：

2.多重分级铰链技术半固态凝胶形态，维持时间更久。

3.我们专利的优势：突破传统铰链技术的局限性，杜绝维持时间短，塑性不理想的弊端。

希雅德分大中小三种分子

【希雅德AII】适用于鼻部，下巴，深层填充(大分子）1mlx1

希雅德ALL是整个系列中最硬的。我们的大多数亚洲医生都将它用于垫鼻梁，丰下巴等需要塑形的部位。当在鼻梁上注射大分子的时候，随着时间慢慢吸收的情况下，希雅德不会像别的品牌的玻尿酸一样鼻梁会变宽，希雅德一直会维持原本直挺的形状。希雅德可以维持约1到2年。在各大韩国品牌的玻尿酸当中，希雅德也叫韩国版丝丽，因为硬度够，是唯一一个韩国品牌的玻尿酸有着丝丽一样骨感的效果，但丝丽因含有甘露醇所以不容易被溶解酶所溶解，但海德却可以快速被溶解酶所溶解。

【希雅德MID】适用于苹果肌，法令纹，太阳穴，额头，面颊，深度皱纹等（中分子）1mlx1

【希雅德Fine]适用于卧蝉，泪沟，丰唇，面部浅度皱纹（小分子）1mlx1

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美乐桃心祛斑针治疗黄褐斑技术原理和操作方法

by admin // 2018年7月14日 // No Comments

为什么会产生黄褐斑？什么是黄褐斑？

黄褐斑是一种常见的获得性皮炎，由浅褐色至深褐色的斑点和斑块组成，涉及面部和颈部的阳光照射区域。这种疾病通常在女性中观察到，男性仅代表10％的病例; 然而，这种疾病的临床组织学特征在两性中都是相同的。虽然黄褐斑的确切原因尚不清楚，但遗传易感性，紫外线（紫外线）照射，怀孕，性激素，避孕药，甲状腺疾病，化妆品，光毒药物（如抗癫痫药物）等因素已被确定为一些常见诱发黄褐斑的促成因素。

美乐桃心祛斑针前后对比图

对于黃褐斑使用不同的治療方式也很难彻底清除，包括使用防曬，色素減退劑和激光療法。有的疗法甚至使用漂白劑與其他療法一起開處方，如維甲酸，外用皮質類固醇或表面剝離劑，但是这对皮肤伤害大，副作用也大。近來，一些研究人員發現了氨甲環酸（TA）對黃褐斑病變有抑製作用，也可以防止紫外線引起的色素沉著。

氨甲环酸祛斑

黑色素合成的主要成因是作為纖溶酶活性的結果，花生四烯酸（AA）（前列腺素的前體）和α-黑素細胞刺激激素的水平的細胞內釋放增加从而导致黑色素的合成。因此，氨甲環酸的抗纖溶酶活性化被認為是該藥物对于抑制黑色素合成的主要機制。局部顯微注射氨甲環酸的臨床試驗結果證明成效明显，在顯微注射氨甲環酸後8週，觀察到患者黃褐斑面積和嚴重程度指數（MASI）評分顯著降低，無明顯副作用。

美乐桃心淡斑精华是韩国BR研究所的VITA C COMPLEX FORMULATION技术特别研发的完美Anti-Melasma疗法, BR Pharm以治疗皮肤处方成分为基础研究开发，主要原料为氨甲环酸，止血环酸，维他命C，烟酰胺，曲酸等有效成分，可以均匀肤色和降低来自光老化的皮肤损害，因为对渴望健康皮肤的患者带来最大的满意度。专门针对黄褐斑，雀斑，晒斑等色素沉着和不均匀肤色而研发的淡斑美白治疗方案，有效抑制黑色素产生，对治疗大部分女性都有的黄褐斑有明显效果。

研究表示，美乐桃心淡斑精华里面的主要成分止血环酸和氨甲环酸是美白针的主要成分，也是治疗黄褐斑最安全而无副作用的有效治疗方案。淡斑效果是为他C的50倍，AHA的10倍。比起美白针通过静脉注射从而作用于患部，美乐桃心独特VITA C COMPLEX技术可使产品通过局部注射，电动微针的方式直接作用于患处，更能有效抑制黄褐斑，雀斑等斑点问题。氨甲環酸（TA）具有增白效果，特別是對於紫外線誘導的色素沉著過度，包括黃褐斑有显著的抑制作用。根据美国国家生物技术信息中心研究显示，氨甲環酸溶液的有效性和安全性，並將其與對苯二酚和地塞米鬆的聯合溶液進行比較，作為女性黃褐斑的黃金標準治療方法。这项研究是一項為期12週的雙盲試驗，在伊朗伊斯法罕進行。 50名伊朗黃褐斑患者在面部的一側施用3％氨甲環酸局部溶液，並且在另一側每天兩次施用3％氫醌+ 0.01％地塞米鬆的局部溶液。在基線時評估黃褐斑面積和嚴重程度指數（MASI）和副作用，並且在皮膚科醫生將要比較的照片之前和之後每4週評估一次。患者滿意度記錄在第12週。研究结果显示，患者和研究者對兩組間黃褐斑改善的滿意度無差異（P <0.05）。然而，與氨甲環酸相比，對苯二酚+地塞米鬆的副作用顯著（P = 0.01）。該研究的結果將氨甲環酸局部溶液作為治療黃褐斑的有效且安全的藥物。

美乐桃心淡斑精华的止血环酸成分有助维持透明的皮肤，抑制黑色素的产生，对于黑痣，雀斑和色素沉着有显著的疗效。止血环酸更可以调节皮肤的PH值，调节碱性和弱碱性，有助于维持健康的皮肤。更对受损的皮肤进行调理，给下垂的皮肤赐予弹性，赐予皮肤活力。维他命C是水溶性产品，普通的维他命C遇到光会急速失效，变色和变质，BR PHARM的独有VITA C COMPLEX技术抑制维他命C氧化，更能有效让产品做出针对性治疗。美乐桃心淡斑精华抑制把帮助Tyrosine酪氨酸变化为melanin黑色素反应的tyrosinase酪氨酸酶，防止melanin黑色素形成，从而平均减少色素沉着而获得光亮的皮肤。

美乐桃心的作用原理

阻断黑色素细胞生成的传达物质纖溶酶，防止其活性化从而抑制黑色素产生。
防止黑色素细胞内黑色素的生成，抑制络氨酸酶的活动。
对于分布广泛的肝斑更能减少现有黑色素，助于淡化其颜色。
抑制被角质形成细胞诱导的黑色素合成。
促进皮肤内的光感因子，打造自然透明的皮肤

美乐桃心正确使用流程

深层清洁脸部，消毒皮肤
一次根据使用范围决定使用量，通常脸部为一小瓶。开封铝盖后，可使用针管把产品抽出，直接涂抹于脸部，避开唇部和眼周。
可使用离子导入仪导入，也可以使用MTS电动微针全脸打圈导入。
操作完毕后使用LED黄灯照射20分钟。
敷上感铭纳米生物纤维再生面膜20分钟作镇静管理。
收尾清洁工作，涂抹术后防晒。

美乐桃心使用方法

电动微针，微针滚轮
电离子导入
混合水光作水光注射
超声波导入
LED光动力疗法

美乐桃心正确使用量

一周一次，建议五次一疗程，可根据患者皮肤状态调整次数
美乐桃心原液2.5ml混合医用蒸馏水或者生理盐水，建议1:1比例混合使用
不混合生理盐水单独操作美乐桃心淡斑针对于敏感皮肤有一定刺激性，建议混合使用

美乐桃心淡斑前后对比图

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PDT焕肤光动力祛痘疗法技术原理与正确操作流程

by admin // 2018年7月14日 // No Comments

PDT photodynamic therapy用于光动力治疗的PDT焕肤祛痘疗法

PDT焕肤是一种无副作用的光敏剂，配合使用欧米茄LED光源治疗痤疮，它被称为PDT光动力祛痘疗法。比起传统ALA成分的光敏剂产品，这是PDT痤疮治疗的新概念，利用皮肤蛋白质组分色氨酸杀死细菌并释放副产物氨基酸。没有灼伤，没有疼痛，没有晒黑，没有副作用！现在您可以体验PDT焕肤有效治疗痤疮。除了脸部以外，PDT焕肤也可以用在后背，不需要繁琐的MTS电动微针导入，不需要调和产品消耗大量时间，只需要涂抹上皮肤后配合LED光源就可以治疗。脸部或身体，只要有痤疮部位面积将不再麻烦，治疗更为快捷与方便！

PDT焕肤光动力祛痘

什么是PDT Acne treatment光动力疗法？

光动力疗法（PDT），有时称为光化学疗法，是一种涉及光和光敏剂的光疗法。 PDT已被证明能够杀死微生物细胞，包括细菌，真菌和病毒。 PDT焕肤广泛用于治疗痤疮。这种治疗特别适用于对其他治疗无反应的严重痤疮病例。光动力治疗（PDT）对于其他皮肤病症，如晒伤皮肤，癌前期细胞和皮肤感染也有作用。 PDT焕肤光动力疗法还可以减少皮肤上产油腺体的大小和活性，称为皮脂腺。这些腺体的过度活跃和炎症都会令痤疮更为严重。比起非发炎中的痤疮，PDT焕肤往往对于炎症痤疮更为有效果

传统叶绿素ALA氨基酮戊酸成分的光敏剂祛痘原理：

5-氨基酮戊酸(ALA)，本品是一种内源性的生化物质经ALA脱水酶及一系列酶促作用，生成具有强光敏作用的原卟啉Ⅸ（PPⅨ）。PPⅨ的合成速度取决于本品拾成速度，而本品又受游离血红蛋白浓度的反馈调节，外源性的本品可绕过反馈抑制系统，使细胞合成聚起足量的PPⅨ。用420～640nm光辐射含有PPⅨ的痤疮，在能量转移过程中产生单态氧（-O2），这种态氧达到一定浓度时可以引发细胞死亡（光毒性）。

副作用：使用ALA治疗时，对其周围的正常组织也会无选择性的破坏，如氧化蛋白、脂质体和其他皮下细胞结构，因此在本品超载的病理条件下生成的氧自由基会导致急性周期性卟啉症。此外本品会引起铁蛋白中铁离子释放，加重对细胞的氧化，也就导致急性周期性卟啉症。部分人会出现红斑和肿胀。ALA氨基酮戊酸也会引发色素沉淀，就是治疗过程中部分人会出现反黑现象。

新概念PDT GEL核黄素与色氨酸治疗原理

在PDT photodynamic therapy中，photosensitizer光敏剂是重要的

1.核黄素受到蓝光照射后激活色氨酸，形成活性自由基。

2.活性自由基与水分子化学反应，再产生ROS

3.ROS具有减少痤疮细菌和皮脂分泌的作用

4.在色氨酸影响后，副产物迅速分解作为氨基酸通过皮肤中的代谢途径排出

5.从而不导致任何副作用，不需担心红肿，灼热感或者晒黑

PDT光动力祛痘原理

PDT焕肤优于其他祛痘疗法的因素包括：

杀死皮肤上的致痤疮细菌
操作更为方便简单，无需调和产品无需电动微针
只影响目标细胞，有助于维持皮肤的完整性
减少皮脂腺的大小和活动
帮助淡化老痤疮疤痕
不会造成疤痕
治疗可能与痤疮同时发生的其他皮肤病症，如老年斑和红斑痤疮
如果需要，可以和药物一起使用，但异维A酸（维甲酸）

PDT焕肤光动力疗法的另一个重要好处是它不涉及使用抗生素或口服类维生素A，如维甲酸。这使PDT焕肤成为不能服用这些药物的人的可行治疗方法。

正确使用说明

1.使用PDT焕肤前清洁并消毒皮肤

2.挤干净脸上的痘痘（使用针轻轻刺破痤疮部位并挤出脓液）

3.取下产品盖子并更换为封闭的锥形盖

4.将PDT焕肤精华涂抹在脸上，避开眼周嘴唇

5.用保险膜盖住脸部，眼周嘴唇留空

6.将毛巾盖在脸上20分钟阻隔光源让产品充分渗透，在亮灯的房间操作的话需要关灯

7.打开415nm，635nm脉冲的LED灯，每个脉冲照10分钟

8.完成治疗，清洁皮肤

9.将感铭生物纳米纤维术后修复面膜放置20分钟

10.术后一定要涂防晒霜，治疗期间都需要注意防晒

PDT焕肤光动力祛痘通常3到5次为一个疗程，取决于每个患者的皮肤状态。每次治疗间隔为一周，但可以根据患者的皮肤状况作调整。进行PDT焕肤的时候也可以与其他治疗同时进行。

使用后注意事项：

1. 当天可洗脸或者轻度化妆

2. 使用当天晚上请温和清洁脸部避免刺激皮肤

3. 光动力治疗期间请尽量隔离紫外线，做好防晒工作

4. 使用后2-3天内请不要进行桑拿，剧烈运动等让身体发热的活动

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Tranexamic Acid Injection for Melasma Treatment

by admin // 2018年7月3日 // No Comments

Injection Melasma Treatment with Tranexamic Acid & other ingridents

What s Melasma?

Melasma is a common skin problem. It is a common acquired dermatitis of light to dark brown macules and patches involving the sun-exposed areas of the face and neck. Most people get it on their cheeks, bridge of their nose, forehead, chin, and above their upper lip. It also can appear on other parts of the body that get lots of sun, such as the forearms and neck.

The cause of Melasma

It isn’t totally clear what causes melasma. Darker-skinned individuals are more at risk than those with fair skin. Estrogen and progesterone sensitivity are also associated with the condition. Some factors such as genetic susceptibility, ultraviolet (UV) light exposure, pregnancy, sex hormones, contraceptive pills, thyroid disease, cosmetics, phototoxic drugs (e.g., antiseizure medications) have been identified as some common contributing factors in developing melasma. Additionally, sun exposure can cause melasma because ultraviolet rays affect the cells that control pigment (melanocytes).

What is Tranexamic Acid?

Tranexamic acid is a procoagulant agent that is approved by the US Food and Drug Administration for treatment of menorrhagia and to prevent hemorrhage in patients with hemophilia undergoing tooth extractions. Through its inhibitory effects on the plasminogen activation pathway, tranexamic acid also mitigates the UV radiation–induced pigmentation response. Systemic tranexamic acid has consistently been reported as an effective treatment of melasma.

How does Tranexamic Acid effects melasma?

The intracellular release of arachidonic acid (AA), a precursor of prostanoid, and the level of alpha-melanocyte-stimulating hormone increase as the result of plasmin activity. These two substances can activate melanin synthesis. Therefore, the anti-plasmin activity of tranexamic acid is thought as the main mechanism of hypopigmentory effect of this agent. The result of a clinical trial of localized microinjection of tranexamic acid proved to be promising. Tranexamic acid exerts effects on pigmentation via its inhibitory effects on UV light–induced plasminogen activator and plasmin activity. UV radiation induces the synthesis of plasminogen activator by keratinocytes, which results in increased conversion of plasminogen to plasmin. Plasminogen activator induces tyrosinase activity, resulting in increased melanin synthesis. The presence of plasmin results in increased production of both arachidonic acid and fibroblast growth factor, which stimulate melanogenesis and neovascularization, respectively. By inhibiting plasminogen activation, tranexamic acid mitigates UV radiation–induced melanogenesis and neovascularization. There is a clinical trial proved that tranexamic acid injections has a promising result for reducing melasma. Significant decrease in the Melasma Area and Severity Index (MASI) score with no significant side effects was seen after 8 weeks of microinjection of tranexamic acid.

What is Melatocin Melasma Treatment?

Melatocin Essence is the perfect Anti-Melasma therapy developed by VITA C COMPLEX FORMULATION technology by BR Research Institute of Korea. The main ingredients of Melatocin Essence are tranexamic acid, hemostatic acid, vitamin C, niacinamide, kojic acid, etc. These formulas can even out skin tone and reduce skin damage from photoaging, provides the greatest satisfaction for patients who are eager for healthy skin.

Melatocin Essence is specifically desig for the treatment of chloasma, freckles, pigmentation and uneven skin tone. Melatocin Essence can inhibit melanin production effectively, it has a significant effect on the treatment of melasma.

According to the study, the main components of Melatocin Essence, hemostatic acid and tranexamic acid are the most effective treatment for treating chloasma without side effects. The effect of anti-melasma is 50 times of Vitamin C and 10 times of AHA. The unique VITA C COMPLEX technology can make the ingredients directly act on the affected part through local injection and electric microneedle, which can effectively inhibit the development of dark spots.

Melatocin Essence Principle of action

Blocks the melanocyte-producing substance plasmin, preventing its activation and inhibiting melanin production.
Prevents the production of melanin in melanocytes and inhibits the activity of tyrosinase.
It can reduce the existing melanin and help to dilute its color.
Inhibition of melanin synthesis induced by keratinocytes.
Create natural and transparent skin.

Melatocin Essence process

Deep cleansing of the face, disinfecting the skin
One vial each treatment on the face. Apply it directly to the face, avoiding the lips and the eye area.
It can be apply using an iontophoresis skin care device or apply using a MTS electric microneedle.
After the procedure, use the LED yellow light for 20 minutes.
Apply Glamour Bio-Cellulose repair mask for 20 minutes for skin clamming.
Finish the cleaning work and apply sunscreen after procedure.

Melatocin Essence application method

Electric micro needle, micro needle roller
Electron iontophoresis device
Mixed with skin boosters for mesotherapy
Ultrasonic device
LED photodynamic therapy

Melatocin Essence Dosage

Once a week, it is recommended to have five treatments, which can be adjusted according to the patient’s skin condition.
Each vial of 2.5ml mix with distilled water or saline, it is recommended to mix 1:1 ratio.

Caution:

Please apply sunscreen during the treatment period.

Do not go to sauna or excises within 2 days after treatment.

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Melasma injection treatment : Melatocin Essence for Melasma Treatment

by admin // 2018年7月3日 // No Comments

Melatocin Injection for melasma treatment

What is Melasma and how did it developed?

Melasma is a common acquired dermatitis of light to dark brown macules and patches involving the sun-exposed areas of the face and neck. This disease is commonly observed in women. Men represent only 10% of cases; however, the clinicohistologic characteristics of the disease are same in both sexes. Although the precise cause of melasma remains unknown, some factors such as genetic susceptibility, ultraviolet (UV) light exposure, pregnancy, sex hormones, contraceptive pills, thyroid disease, cosmetics, phototoxic drugs (e.g., antiseizure medications) have been identified as some common contributing factors in developing melasma.

It is also difficult to completely eliminate melasma. There are different treatments for chloasma, including the use of sunscreens, hypopigmenters and laser therapy. Some therapies even use bleach to prescribe with other therapies, such as retinoic acid, topical corticosteroids or topical strippers, but such treatment might cause skin damage and side effects. Some researchers have discovered that tranexamic acid has an inhibitory effect on melasma lesions and also prevents ultraviolet-induced pigmentation.

The progream is specifically desig for the treatment of chloasma, freckles, pigmentation and uneven skin tone. Melatocin Essence can inhibit melanin production effectively, it has a significant effect on the treatment of melasma.

research

Melatocin Essence Principle of action

Blocks the melanocyte-producing substance plasmin, preventing its activation and inhibiting melanin production.
Prevents the production of melanin in melanocytes and inhibits the activity of tyrosinase.
It can reduce the existing melanin and help to dilute its color.
Inhibition of melanin synthesis induced by keratinocytes.
Create natural and transparent skin.

Melatocin Essence process

Deep cleansing of the face, disinfecting the skin
One vial each treatment on the face. Apply it directly to the face, avoiding the lips and the eye area.
It can be apply using an iontophoresis skin care device or apply using a MTS electric microneedle.
After the procedure, use the LED yellow light for 20 minutes.
Apply Glamour Bio-Cellulose repair mask for 20 minutes for skin clamming.
Finish the cleaning work and apply sunscreen after procedure.

Melatocin Essence application method

Electric micro needle, micro needle roller
Electron iontophoresis device
Mixed with skin boosters for mesotherapy
Ultrasonic device
LED photodynamic therapy

Melatocin Essence Dosage

Once a week, it is recommended to have five treatments, which can be adjusted according to the patient’s skin condition.
Each vial of 2.5ml mix with distilled water or saline, it is recommended to mix 1:1 ratio.

Caution:

Please apply sunscreen during the treatment period.

Do not go to sauna or excises within 2 days after treatment.

218 total views, 1 views today

BUY Meditoxin Botulinum Toxin Online | Meditoxin suppliers | Botox wholesalers

by admin // 2018年6月27日 // No Comments

BUY Meditoxin Online from Meditoxin suppliers & Botox wholesalers

Meditoxin is a botulinum toxin type A complex (100 Units) pharmaceutical manufactured by Medy-Tox Inc. and officially launched in Korea since 2006.

Throughout the 1980s and 1990s, Clostridium botulinum had been intensively researched by a group of scientists in Korea. In 2000, the scientists established a biotech venture named “Medy-Tox Inc.” which specializes in botulinum and its toxins. Following much research on biological, biochemical, immunological and toxicity aspects, botulinum toxin type A has been developed as a biopharmaceutical product. Meditoxin buy online from botox wholesalers!

Buy Meditoxin online

In 2004 and 2005, Meditoxin® has been licensed to famous pharmaceutical companies including Ranbaxy which is one of the biggest generics companies in the world and a Korean pharmaceutical company, CJ Corp., which will launch Meditoxin® in the Latin America of more than 50 countries. Furthermore, Q-MED has been the marketing and distributorship partner of Meditoxin® for Europe and Japan since early 2007. All these licensing cases show the credibility of Meditoxin®

MEDITOXIN®, the First Choice of Botulinum Toxin Type A Pharmaceutical has the best value proposition in terms of its price and quality. MEDITOXIN® is a biosame form of Botox® (Allergan, USA).

It appears as a lyophilized white powder for injection in a colorless transparent vial.

Expire date will be 36 months from the manufacture date.

The unopened lyophilized vial should be stored in a freezer (below -5 degree) or refrigerator (2-8 degree)

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Buy 100U Botulax Botulinum Toxin Type A Online

by admin // 2018年6月26日 // 10 Comments

100U Botulax Botulinum Toxin Type A

Botulax is made in Korea by Hugel Pharma. The advantages of Botulax is that Botulax is strictly controlled for safety and high stable potency, has purity of 99% and safety & efficacy have been successfully proved compared with Botox. Botulax contains 100 units (U) of Clostridium botulinum toxin type A, 0.5 milligrams of albumin (human)and 0.9 milligrams of sodium chloride in a sterile, vacuum-dried from without a preservative. Most of the professionals buy Botulax Botulinum Toxin online from Korean botox wholesalers nowadays to use in their own country, it’s another choice compare to botox.

It appears as a lyophilized white powder for injection in a colorless transparent vial.

Expire date will be 36 months from the manufacture date.

The unopened lyophilized vial should be stored in a freezer (below -5 degree) or refrigerator (2-8 degree)

Buy Botulax Botulinum Toxin Online

Characteristics of Botulax:

Higher specific activity than those of other company’s botolinum toxin products by improving lyophilization process

Botulinum toxin type A neutroxin: purified from Clostridium botulinum type A

Albumin: Human serum albumin,bulking and stabilizing agent and adhesion reducer.

KP grade NaCl: Bulking agent and keeping isotonicity during formulation

KP grade Developmental status:

2007.5: reported nonclinical study

2008.3: reported clinically study Phase l

2009.7: Finished Phase lll clinically study

Facility: GMP approved by KFDA

Buy Botulax Botulinum Toxin online

Features of Botulax Botulium Toxin Type A

Excellent Effect – Result appeciable improvement
Simple Procedure – Just by few tiny injections
Short Treatment – 10 minutes, as short as a tea break
No Down Time – Resume normal work right away
Fast Onset- Take only 2 to 3 days to see noticeable effect
Outstanding Efficacy – Over 98% users satisfied with the Botulax® treatments
Proven efficacy & Safety – The efficacy and safety of Botulium Toxin Type A are proved and verified to be comparable to botox in clinical studies.
Global Product – Global Product, Botulium Toxin Type A has been sold in over 25 countries.
Guarateed Safety – Approved by Health Authorities with over 10 years’ clinical practices.
Applications/Indications

Not just cosmetic Botox, Botulium Toxin Type A also has therapeutic applications, Botulium Toxin Type A is used for the treatment of benign essential blepharspasm in patients 18 years of age and above. For the treatment of equinus foot deformity due to spasticity in pediatric cerebral palsy patients 2 years of age and above. And as many know Botox, for temporary improvement of serious glabellar wrinkles ranging from moderate to severe associated with corrugators muscle and/or procerus muscle activities in adults over the age of 18 and below the age of 65. The vials are generally stored in a freezer or refrigerator and they retain a shelf life of 24 months.

Dosages

For blepharospasm the initial recommended dose is 1.25 – 2.5 U (0.05 mL to 0.1 mL volume at each site) injected into the medial and lateral pre-tarsal orbicularis oculi of the upper lid and into the lateral pre-tarsal orbicularis oculi of the lower lid. For pediatric cerebral palsy, a total dose of 4U/kg bodyweight is recommended for the affected gastrocnemius muscle in patients with hemiplegia. And in patients with diplegia, the recommended dose is 6U/kg bodyweight divided between both legs. The maximum dose administered must not exceed 200U/patient at a time. For Glabellar wrinkles reconstituted sterile saline. 20U is used and there are additional application instructions for best practice, actual amounts vary on the presentation of the client.

Effects

In Blepharospasm, the effects should appear within three days and peak after three weeks. For pediatric cerebral palsy applications, the expectation is improvement within four weeks of the injection. The effects vary for glabellar wrinkles due to the usually individualized dosages.

Precautions

There is the possibility of reactions at the site of an injection, and effects beyond the injection site, including but not limited to asthenia, generalized muscle weakness, diplopia, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence and breathing difficulties. Serious hypersensitivity has been reported as rare. There is a caution for people with pre-existing neuromuscular disorders, and for those with corneal exposure and ulceration in blepharospasm. Botulium Toxin Type A is not to be administered at all if a patient has a known allergy to any of the ingredients, or if the patients have neuromuscular junctional disorders or known to have adverse reactions. They should not be administered while taking muscle relaxants and some antibiotics. Further, the actual effects of prolonged use are not entirely explored. There is also additional advice for the specific therapeutic conditions mentioned, as this description is not comprehensive.

In the case of overdose

In the case of an overdose it has been advised that effects may not be immediate. It is further advised that the patient be monitored for muscle weakness and/or paralysis for a period of weeks after the occurrence. There is an anti-toxin available but the caution with the anti-toxin is that it will not reduce any already apparent effects.

Buy Botulax Botulinum Toxin Online

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海恩PDRN再生美塑，DNA细胞疗法与水光嫩肤合二为一

by admin // 2018年6月19日 // No Comments

海恩PDRN再生美塑，DNA细胞疗法与水光嫩肤合二为一

PDRN美塑是由称为聚脱氧核糖核苷酸（PDRN）的生物分子组成的复原皮肤治疗。 PDRN分子是由13个或更多个脱氧核糖核苷酸单体组成的聚合物。核苷酸是在DNA或RNA中发现的单体结构单元，脱氧核糖核苷酸是由脱氧核糖糖类构建的核苷酸。从鲑鱼的睾丸中获得DNA提取物，然后片提炼转化成PDRN。

PDRN在整个治疗期间产生显着的组织改善和一致性。由于PDRN具有促进皮肤移植后恢复的特殊能力，PDRN在2008年获得批准的PDRN后首次在意大利用作组织修复化合物。 PDRN可以用于美塑疗法，因为它可以刺激皮肤细胞的代谢活动以再生胶原蛋白，葡糖胺聚糖和糖蛋白。 PDRN通过促进抗增殖和增加成纤维细胞生长速度刺激伤口恢复。这意味着PDRN可以唤醒疲惫的老年细胞，使其更年轻，并重新开始工作。 PDRN美塑使皮肤弹性，质地和水合作用显着改善。 PDRN也被称为韩国婴儿针，已通过皮肤科诊所证明其有效且安全，可用于细胞生长和组织再生。

韩国婴儿针

海恩PDRN再生美塑

前几年水光美塑发展在韩国并成为亚洲最热门的皮肤再生疗法，现在韩国美容界又研发了最新技PDRN美塑，在当地也被称为海恩PDRN再生美塑或DNA再生疗法，最近这几年已成为韩国皮肤诊所，整形外科最热门的治疗方法之一。这款将PDRN和透明质酸两者结合在一起的新技术，海恩PDRN再生美塑不但令皮肤逆齡恢复活力，减淡细纹和增加胶原蛋白，还可以有着水光美塑一样让皮肤变得水润光滑。这种把传统PDRN和水光合二为一的新技术，让广大爱美者的皮肤可以得到多方面的改善。

透明质酸作用机理

透明质酸是我们身体的一部分，严格来说，应称其为“增湿剂”更确切。表皮是皮肤最外层的保护屏障，通常其含水量为20%～35%。伴随着衰老，透明质酸在皮肤中的含量也随之减少，从而出现皮肤细纹，失去弹性。通过导入和涂抹适量的透明质酸，可以增强皮肤弹性、保持水润，恢复年轻。透明质酸除了对正常的皮肤具有保湿作用外，对创伤的皮肤还具有促进愈合的修复作用。透明质酸能够吸收和储存1000倍于透明质酸重量的水分在皮肤中。由于透明质酸的高保湿和水化性能，可通过旷大胞间空隙，促进修复细胞的移动，促进和维持伤口周围皮肤水环境的恒定，激活皮肤屏障自我修复能力。透明质酸，是目前最好的保湿成份。市面上绝大多数具有保湿功能的护肤品中，主要成份就是它。

PDRN（多聚脱氧核糖核苷酸）作用机制

PDRN刺激并增加皮肤中称为成纤维细胞的细胞的代谢活性，从而再生皮肤的关键组分如胶原蛋白，糖胺聚糖和糖蛋白。 PDRN激活疲惫的老年和受损细胞，使其更年轻，并重新开始工作。它也可以机械地作为细胞和细胞外基质的支架生长 – 它们具有三维结构，其中成纤维细胞可用于产生其再生作用。此外，它还为DNA合成提供了构建模块。通过补救途径，多核苷酸被身体的过程分解为嘌呤和嘧啶，然后再循环到新的DNA中。多聚脱氧核糖核苷酸（PDRN）含有50-2000个碱基对组合在链中的脱氧核糖核苷酸聚合物，已知通过激活A2亚型嘌呤能受体和补救途径来加速细胞增殖。 PDRN有助于皮肤和组织的再生，它也可用于糖尿病足溃疡的临床治疗。由于它有助于皮肤再生，它可以在激光治疗后使用。韩国药监局KFDA于2008年通过PDRN用于组织修复和皮肤移植创伤的治疗。 PDRN之前已经被批准在意大利临床使用，作为组织修复刺激剂。

海恩PDRN再生美塑对皮肤的作用：

改善皮肤弹性

改进的水合作用

减少细纹和皱纹

皮肤修复 – 改善皮肤屏障功能

皮肤正常化 – 皮肤增厚

改善肤色

改善皮肤纹理

改善皮肤炎症

海恩PDRN美塑使用方法

外部应用，可结合最先进的技术：水光美塑，电动微针，微针滚轮，射频针，脉冲光和美容导入仪。

hp nuclei vital pdrn

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Mesotherapy Treatments for skin rejuvenation

by admin // 2018年6月18日 // No Comments

Mesotherapy Treatments | Mesotherapy Products | Aqua Lifting Injection

Cosmetic procedures have undergone a huge revolution in the last few years, thanks to the advancement of science and technology. Mesotherapy is one such cosmetic procedure that has been used in the last few years for many types of skin treatments. In this article, we are going to see about the basics of mesotherapy Treatments and how it is used for skin rejuvenation.

What is mesotherapy treatment and how does it work for facial rejuvenation?

Mesotherapy is a cosmetic treatment that was first used to reduce excess body weight. We also called it Lipodissolve Mesotherapy treatment. Injections filled with FDA approved medicines, and other nutrients were injected into the patient’s body to reduce problems like excess body weight and cellulite. We also called it fat dissolving treatment or Lipolysis Injection. Gradually, the process was also used to make one’s skin tighter and younger than before, by rejuvenating the areas around one’s face and neck.

Old age, heredity issues, stress and other factors lead to our skin becoming saggy and wrinkled. Yes, there are lots of facial creams and packs available, but they are only temporary quick-fixes. If you are looking for a treatment that restores the vitality and glow in your skin, mesotherapy is one of the best treatments for you. Hyaluronic Acid is one of the main ingredients that keep the skin young and fresh always. In the mesotherapy treatment, injections filled with Hyaluronic Acid skinboosters are injected into the skin on the face/neck. As a result, it results in the increased elasticity of one’s skin, keeping the skin around the face and neck as rejuvenated as possible.

Types of products used for mesotherapy to bring about facial rejuvenation

Mesotherapy for facial rejuvenation is mainly done for the following reasons:

To make skin looking young and bright
To keep skin moisture
To reduce wrinkles, dark spots, and other ageing symptoms
To reduce skin sagging and make skin look firm and tight

1. Hyaluronic Acid (Main Component)

Hyaluronic Acid has amazing water-binding ability that absorbs and stores the moisture of 1,000 times of the weight of Hyaluronic Acid in the skin. It plays an important role in preserving storing as well as spreading nutrients to the skin. Thus, Hyaluronic Acid is an essential ingredient for moisturizing, hydrating, and radiant glowing skin.

2. Adenylic Acid (Added Component to Hyaluronic Acid)

Adenylic Acid is a peptide compound that is used to reduce the appearance of wrinkles. When it comes to fine lines and wrinkles on the face, especially around the eyes and mouth; they usually form because of repeated facial expressions, such as smiling, frowning, or furrowing the brow in deep concentration of frustration. Adenylic Acid acts a powerful anti-aging agent that works by causing facial muscles to relax, minimizing, fading crow’s feet, fine lines and wrinkles and improve skin elasticity.

3. Botox (Added Component to Hyaluronic Acid)

Botox blocks signals from the nerves to the muscles. The injected muscle can no longer contract, which causes the wrinkles to relax and soften. It is most often used on forehead lines, crow’s feet (lines around the eye) and frown lines. It could be dilute with more saline and mix with Hyaluronic Acid, be careful with the amount, too much can cause your facial expression to look stiff.

4. Glutathione (Added Component to Hyaluronic Acid)

Glutathione is often know as Body’s Master Anti-Oxidant. It composted of three amino acids – cysteine, glycine, and glutamate. Glutathione excels in prevent as well as suppress the melanin pigments. It has an excellent effect of whitening and this explain why Glutathione is effectively used to treat dull complexion, uneven skin tone, and acne scars. In addition, Glutathione also known by its self-repairing ability of restoring the damaged cells by ultraviolet rays, the antioxidant effect of skin aging, and the effect of reducing acne.

5. EGF (Added Component to Hyaluronic Acid)

EGF encourages collagen production and stimulates elastin fibroblasts for youthful, radiant and glowing complexion. Research shows that it plays an important role in repairing wounds and improving skin conditions.

6. PDRN ( Can be inject alone or can be added Component to Hyaluronic Acid)

PDRN produces significant tissue improvement and consistency throughout the treatment period. PDRN was first deployed as a tissue repairing compound in Italy after approved PDRN in 2008 due to its special ability to accelerate recovery after skin grafts. PDRN can be use with mesotherapy processes because it can stimulate the metabolic activity of cells in the skin to regenerate collagen, glycosaminoglycans and glycoproteinswound. PDRN stimulate wound recovery through antigenesis enhancement and boost rates of growth in fibroblasts. Which means PDRN can awaken tired aged cells to act younger and get to work again. PDRN Mesotherapy makes a significant improvement in skin elasticity, texture and hydration. PDRN injection is a rejuvenating skin treatment made of biological molecules called Polydeoxyribonucleotide (PDRN). A PDRN molecule is a polymer consisting of 13 or more deoxyribonucleotide monomers. A nucleotide is a monomer building blocks found in DNA or RNA and Deoxyribonucleotide is a nucleotide built from deoxyribose sugars.The DNA extract is obtained from the testis of salmon, then fragmented into PDRN.

How does the mesotherapy treatment works?

The entire process involves four sessions that are conducted every once a month. In all these sessions, injections filled with hyaluronic acid and other vital nutrients are injected very carefully into the mesoderm, the layer which is found beneath the skin. The ingredients that are injected into the skin may slightly vary based on the nature of the patient’s skin, the severity of sagging problems and the like.

During the first session, an equal mixture of hyaluronic acid, and mesolift cocktail (Adenylic Acid, Botox, Glutathione, PDRN, EGF, etc depends on the result patient wanna acheive) is injected into the mesoderm. Injections containing these ingredients are then repeated every month based on the patient’s skin type and severity of the condition. During a session, a patient may receive one or multiple injections based on the number of nutrients his/her skin needs. For optimum results, it is highly recommended that patients repeat the treatment every two months. Every session takes about 30 minutes to get over.

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