None surgical brow lift with U Cog double needles cannula PDO thread

U Cog Double Needles Cannula PDO threads : none surgical brow lift procedure

U cog PDO thread is linked with two 19G cannula needle at both the end of the spike PDO thread, it is strong enough to pull up sagging skin of the jaw line, especially it could used for none surgical brow lift. This breakthrough product which replaces what was possible only as a major surgery through incision with simple procedure is produced by leading-edge technology of U COG pdo lifting thread. By having two cannulas while pulling from two directions, the strength is strong enough and the lifting effect of the COG thread became much stronger, it could be use for breast lifting, butt lifting, jaw line lifting, forearms around triceps and brow lift. Inserted with its cannula to prevent patient from brushing and swelling.

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Unlike similar products, it is made of 48cm thread so that it can be easily applied to any part and it is filled with high quality spikes cutting throughout the thread. The needle is also specially made and does not break or bend. U COG double cannula pdo lifting thread for none surgical brow lift is mainly applied to the forehead, upper part of each eyebrow so that drooped eyelids can be lifted. So with a single treatment, you may have an effect for enlarging the eyes, for spreading the whole wrinkles of the eye tails and making the forehead smooth.

How to perform a none surgical brow lift with U Cog double needles pdo thread

The size of the thread is  in 21G 110 mm cannula, the thread is 470mm

U-Cog 21G 110mm W-Spatular 470mm USP 0




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SM Numbing topical anesthesia Cream 10.56% Lidocaine 105.6mg Fast Penetration Pain Relief

SM Strong Topical Anesthetic Numbing Cream Fast Penetration Pain Relief

Topical anesthesia contains lidocaine, which is a medication used to to reduce pain in small areas including the skin, nose, and throat. Injection lidocaine is used to treat ventricular tachycardia and to perform nerve block while topical numbing cream is used to used to numb tissue in a specific area. These products are available as gels, sprays, solutions, creams, and ointments. SM Numbing cream is most commonly used to relieve pain caused by waxing, piercing, tattooing, tattoo removal, micro needling, skin boosters injection and laser treatments as well.

SM numbing cream
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Strongest Topical Anesthetic : SM Numbing Cream

SM numbing cream is made in Korea, and it is approved by the KFDA, with 10.56% lidocaine, it is safe to use, it won’t feel burning or allergies compares to other brands or China made products.  10.56% lidocaine provides ultra strong numbing effect, it is the most strongest topical anesthetic numbing cream without any side effects.


White to yellowish cream, 500G, 17.56oz


Store at room temperature between 1 to 30 degrees centigrade.

Shelf life:

3 years from manufacturing date. MADE IN KOREA.


1. Do not apply to the following people:

  • You or your partner oversensitive to lidocaine and or another amide preparation.
  • Anyone with external wound or inflammation on the desired area.
  • Don’t use to a pregnant woman.

2. Extra care needed to the following people, with liver and kidney disease.

3. Warnings of usage:

  • External use only. Avoid contact with the eyes and nose.
  • Recommend NOT to use repeatedly on the same area.
  • Keep out of reach of children
  • Store at room temperature away from light and moisture. Do not freeze.
  • Keep this product away from heat and open flames.
  • For best results, SM Numbing cream should be applied 20 to 30 minutes before the procedure. The anesthetic effect should last about an hour.
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Lidocaine is volatile ingredient.
Please make sure to close the cover tightly every time after using, otherwise anesthetic effect will be less.
Please follow the instruction to maximize the anesthetic effect.

1. Apply thick amount of the cream on the treatment area.
2. Cover the applied area with the plastic wrap to help absorbing lidocaine into the skin.
3. After 25 to 35 minutes, remove the plastic wrap, clean the cream off with cotton and saline water.

Leave the cream on the skin longer for better result, normally 30 minutes will be enough for micro needling, skin boosters injection, laser treatments. If you are doing tattoo, leave it on for more than 45 minutes.
Don’t remove the plastic wrap until you feel the numbing effect.



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Melsmon human placenta injection : Japan’s anti-aging rejuvenation

Melsmon human placenta injection for anti-aging & skin rejuvenation

Melsmon human placenta injection is known as for correction of climacteric symptoms in premenopausal women. Japan’s Melsmon placenta combines the magical power of nature with modern high-tech development to provide you with the best safe and efficient way for you to improve your physical condition, it also focus on your skin & facial rejuvenation. Placenta in Asia has been a traditional medicine in China for over hundreds of years. China’s ancestors have long had experience using placenta, because it has a variety of hormones that are lacking in menopausal women, it is a nutrient for activating cells. In the past, after the birth of the fetus, the placenta that had been removed, removed micro-vessels and water, dried it, and grind it. It was used as a medicine in China, especially for menopausal women or women. Japan with its high technology developled the eastern medicine and turn them into human placenta injection, a more direct way of absorbing the placenta.

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The truth & safety of Melsmon human placenta injection

From the inspiration of the Chinese placenta medicine from old ages, Japan is one of the countries with the longest history of placenta research, with the most complete modern placenta technology, Japan became the manufactory of the placenta products in the world. Japan Melsmon human placenta is a product that has approval of the Japanese Ministry of Health, Labour and Welfare, it is manufactured by Melsmon Pharmaceutical Co., Ltd. Japan Melsmon human placenta injection is rich in a variety of amino acids, active peptides, various growth factors and repair factors, through the body circulation to comprehensively regulate the body’s various functions. Through the circulation of the human body, it can comprehensively regulate various functions of the body, enhance beauty, enhance resistance, regulate endocrine, and delay premature aging and aging of the internal organs. Melsmon also revitalizes energy, people usually feel more energetic after treatment. As a top-notch product in Japan, Melsmon human placenta is frequently favored by political and business elites and entertainers. Melsmon human placenta’s famous name has long been a household name in the domestic beauty industry and among Asia.

The function of Melsmon Placenta


To improve the metabolic process for protein and amino acid and also breaking up of glucose to produce energy. In this respect, the placenta plays the role of a liver.

Respiratory Function

The fetus is unable to respire with the external oxygen directly. Hence it must go through the placenta to exchange the required oxygen with carbon dioxide through the mother’s blood. The function is akin to the lung of a human body.

Excretory Function for Metabolic By-products

The fetus cannot discharge the metabolic by-products by itself. The by-products are channeled to the placenta for processing and this is similar to the function of kidney for an ordinary person.


Producing Hormone

In order to maintain the normal body function during pregnancy, essential hormones must be produced and made available through secretion. During the initial period, the placenta stimulates the mother’s ovary to produce hairy glands and this enhances the secretion of female hormone. In the final stage of pregnancy, it secrets the hormone for ovulation automatically and this is akin to the function of the pituitary gland and the ovary.

Immunity Function

The fetus does not possess any immunity against diseases. Therefore, it has to acquire the antibody from the mother’s body through placenta.

Other Functions

The numerous functions of placenta are beyond the scope of modern medical science. If an organ akin to placenta could be manufactured by artificial means, it will certainly become a great discovery for the world. Unfortunately modern medical science is still unable to do this but more research is being done.

placenta injection
Placenta injection
melsmon placenta injection
Melsmon placenta injection

Main ingredients of Melsmon

1. Nucleic acid:
Nucleic acid is the basic substance in the nucleus of human body. It plays an important role in the growth and proliferation of cells, especially the normal metabolism of skin tissue, the promotion of skin cell viability and the repair of damaged cells. It determines the aging process of cells.

2. Amino acids:
Contains more than 30 kinds of amino acids, including 8 essential amino acids such as cystine, cysteine, leucine, arginine, serine and jiric acid. Amino acids are the basic substances that make up proteins in human cells. Therefore, it is the basic unit of tissue repair, the constituent components of enzymes and hormones, and some of the energy is also derived from them. It plays an important role in the growth and development of adolescents and the health and longevity of middle-aged and elderly people.

3. Natural placental immune protein
Placental tissue fluid is rich in HGG (chorionic gonadotropin), TSH (thyrotropin), prolactin, steroid hormone and antibody protein, especially for women with severe skin aging.  It can improve sexual function, delay the thinning of vaginal mucosa and the relaxation of perineal sphincter. It also heals endocrine disorders caused by menopausal syndrome and irregular menstruation, it improves skin wrinkles, pigment spots and so on. Antibody proteins can improve the body’s resistance to infectious diseases, especially respiratory and digestive diseases.

4. Cell growth factor population
Human placenta is rich in epidermal growth factor (EGF), basic velvet cell growth factor (BFGF), platelet cell growth factor (PDGF), transforming growth factor (TGF), islet cell growth factor (IGF) and Cell growth promoting factor. All of these factors promote the production and division of the corresponding cells. Skin cells, fibroblasts, vascular endothelial cells, smooth muscle cells, etc. are activated and grown. TGF also activates fibroblasts, inhibits the keratinocytes at the outermost layer of the epidermis, and synergizes with the cell growth factor group to significantly improve the skin, improve skin metabolism, and maintain skin radiance.

5. Multi-type collagen and nutrients
This product is rich in multi-type collagen, the skin ageing with the increase of age, the collagen component in the skin dermis is degenerated, the collagen component is reduced, the skin’s toughness and elasticity are reduced. Once when the collagen component is supplement, it will restore the elasticity and toughness of the skin.

melsmon placenta injection
Melsmon placenta injection


  • One treatment contains 50 vials, 1 vial for each injection. Melsmon is apply through subcutaneous injection, and inject 1 vial every two days for the first month, and inject twice a week for the rest.
  • Mix 1 vial of Melsmon with skin booster to inject on the face with Ice shot injector.

Manufacturer: Melsmon Pharmaceutical (Merusumon pharmaceutical) メルスモン製薬

Product Contains: Melsmon Cell Revitalization Extract 100 mg / 1 vial

Packaging: 2 ml x 50 ampoules/ Box

We offer authentic Melsmon which ship from Japan, you can track your package from Japanese EMS

Japan EMS tracking:

melsonmon placenta
Melsonmon placenta

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Liporase Hyaluronidase first aid to dissolve Hyaluronic Acid dermal fillers went wrong

Liporase Hyaluronidase : dissolve hyaluronic acid dermal fillers that went wrong

Liporase Hyaluronidase is made in Korea and it is approve by KFDA. Hyaluronidase is used to dissolve hyaluronic acid fillers that have been placed incorrectly, excessively, or unevenly. It is injected into the same locations that the filler already is. Hyaluronidase is also used in emergency situations where dermal filler has been inadvertently injected into an artery causing occlusion of the blood supply. It is injected into the vicinity of the dermal filler that needs to be dissolved.

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What is hyaluronidase?

Hyaluronidase is an enzyme (compounded by special pharmacies) that causes hydrolysis (breakdown) of hyaluronic acid. It is often referred to as a reversal agent for hyaluronic acid fillers. When the enzyme is injected it dissolves the synthetic hyaluronic acid filler, leaving your own intact. Liporase Hyaluronidase is made in Korea. It is used to dissolve hyaluronic acid based dermal fillers that have been placed incorrectly, excessively, or unevenly. Hyaluronidase is also used in emergency situations where dermal filler has been inadvertently injected into an artery causing occlusion of the blood supply. It is injected into the vicinity of the dermal filler that needs to be dissolved.

1 box : 10 vials

Each vial contains 1,500 I.U. of hyaluronidase to be mix with 3cc of saline.

Uses of Hyaluronidase Injection:

  • To remove filler, hyaluronidase can be injected to dissolve the hyaluronic acid in dermal fillers.
  • To increase the effect of lipodissoving injection, hyaluronidase can be added to the cocktails of fat melting injection.
  • Hyaluronidase is often combined with local anaesthetic to increase the diffusion of local anaesthetic.

Process of Hyaluronidase Injection for filler dissolving:

  • Mix 3cc of saline to 1 vial of Hyaluronidase, it could disslove 3cc of hyaluronic acid.
  • Hyaluronidase is injected, along with lidocaine (and sometimes epinephrine), into the area where the filler needs to be dissolved.
  • Hyaluronic acid filler will start to be dissolve right away, and it will be absorb by the body in a few hours.

Process of adding Hyaluronidase to lipodissolving  injection:

  • Mix 5cc of saline to 1 vial of Hyaluronidaseit could be add to a 10cc lipodissolving Vline injection. If it is 30cc, add 2 vials of Hyaluronidase.
  • Hyaluronidase is mixed with Vline injection, it is injected along with lidocaine into the fat layer evenly.
  • Massage the area where it was treated for 15 minutes each day and 7 days in a roll, apply hot packing after massage.


There have been a few reports that some people may have an allergy to hyaluronidase, which happens to those who are allergic to bee stings.

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Hyaldew long lasting dermal fillers : Korean patented micro bead cross linking technology

Hyaldew dermal fillers : Korean long lasting cosmetic fillers with patented micro beads technology

Hyaldew dermal fillers are manufactured in Korea and is the only Korean hyaluronic acid with CE certified. Hyaldew is also KFDA and GMP certified by Korea, guaranteeing safety and quality. Hyaldew’s unique patented micro-bead cross linking technology is arguably the most influential brand of dermal fillers in Korea. It is exported worldwide to the United States, Europe, China, South America and the Middle East. Hyaldew dermal fillers are the leading product of Korean hyaluronic acid dermal fillers in the world. Hyaldew dermal fillers use 100% hyaluronic acid, without any other additions, using HA multi-stage micro-bead cross linking technology to achieve ultra long lasting result! Hyaldew is made by Bioplus Korea, other famous products of Bioplus such as Glamour skin boosters, Dene B body fillers, and many more!


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Hyaldew dermal fillers patented micro bead cross linking technology

For dermal fillers itself, cross linking technology is the most important step in the history of hyaluronic acid development. Hyaluronic acid with cross linked last much longer. Hyaluronic acid without cross linked is a joint lubricant, such as Hyaron, which is used as skin boosters in China.

Hyaldew dermal fillers patented microbead cross linking technology is another major technological breakthrough in the natural cross linking technology of hyaluronic acid. So what is the difference between artificial cross linking and natural cross linking technology?

In contrast, the artificial cross linking technology has more impurities. Fillers with natural cross linking techonology can be totally absorbed by the body, and nothing remains. It will absorb and decompose with the metabolism of the human body, it doesn’t cause any harm to the body. But fillers with artificial cross linking technology usually cause a lot of remains the body.

Hyaldew dermal fillers, while maintaining the most natural hinges, guarantees the durability of hyaluronic acid with advanced and stable patented bead hinge technology, which not only maintains the 100% natural characteristics of hyaluronic acid, but also solves the short hyaluronic acid maintenance time in the absorption process. The disadvantage of deformation.

Hyaldew dermal fillers has completed an export license at Seoul National University Hospital and passed the strict 5-year clinical trial in Japan, making it the safest and most effective hyaluronic acid product.

Patent cross linking technology introduction:

1. Hyaldew’s three-stage decomposition and combination process:

2. Multi-stage cross linking technology Semi-solid gel morphology, which lasts longer.

3. Advantages of our patent: Breaking through the limitations of traditional cross linking technology, and eliminating the short maintenance time of fillers and unsatisfactory plasticity.

Hyaldew ALL: Suitable for nose & chin augmentation, deep filling (macromolecule) 1 ml x1

hyaldew all dermal fillers
Hyaldew all dermal fillers

The Hyaldew is the hardest in the whole Hyaldew series. Most of our Asian doctors use it for nose & chin augmentation. When injecting Hyaldew All on the bridge of the nose, Hyaldew will not widen the bridge of the nose like other brands of hyaluronic acid, and Hyaldew All will maintain the original straight shape. Hyaldew All can last for about 1 to 2 years. Among the major Korean brands of hyaluronic acid, Hyaldew All is also called the Korean version of Vivacy Stylage XXL, because the hardness of the filler itself, it is the only Korean brand of hyaluronic acid that shapes  Asian nose bridge like Stylage XXL, but Stylage XXL is not easy to be melt by Hyaluronidase because of the mannitol component. Hyaldew can be quickly dissolved by the Hyaluronidase.

Hyaldew MID: Suitable for nasolabial fold, temples, forehead, cheeks, deep wrinkles, etc. (medium molecule)  1 ml x1

Hyaldew Mid dermal fillers
Hyaldew Mid dermal fillers

Hyaldew FINE: Suitable for lips, fine lines, under eye areas etc. (small molecule)  1 ml x1

Hyaldew Fine dermal fillers
Hyaldew Fine dermal fillers

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PDT Photodynamic therapy for acne tutorial : acne treatment with Omega LED light

What is PDT photodynamic therapy acne treatment?

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PDT photodynamic acne  therapy  by using a non-side-effect photosensitizer that works with Omega LED light source to treat acne. It is called PDT photodynamic therapy. PDT GEL is a new concept of PDT acne treatment compared to traditional ALA-based photosensitizers, which use the skin protein component tryptophan to kill bacteria and release by-product amino acids. No burns, no pain, no tanning, no side effects! Now you can experience PDT photodynamic therapy for effective treatment of acne. In addition to the face, PDT gel can also be used on the back or anywhere on your body. Without the need for cumbersome application with MTS electric micro-needle, you don’t need to reconcile the product to consume a lot of time. All you have to do is to apply PDT gel on the skin of the patient along with the Omega LED light source. You can treat your patient’s face or body, as long as there is acne problem. The treatment time is faster and more convenient!

PDT gel photodynamic therapy
PDT gel photodynamic therapy: Buy PDT GEL photosensitizer at gangnam!

Photodynamic therapy (PDT), sometimes called photochemotherapy, is a light therapy involving light and photosensitizers. PDT has been proven to kill microbial cells, including bacteria, fungi and viruses. PDT skin is widely used to treat acne problems. This treatment is especially useful in cases of severe acne that do not respond to other treatments. PDT acne treatment also has effects on other skin conditions such as sunburned skin, precancerous cells and skin infections. PDT Photodynamic Therapy also reduces the size and activity of oil-producing glands on the skin, called the sebaceous glands. Excessive activity and inflammation of these glands can cause more severe acne. PDT photodynamic therapy is often more effective for inflammatory acne than non-inflammatory acne.

What is PDT photodynamic therapy acne treatment?


pdt photodynamic therapy acne treatment for back
Pdt photodynamic therapy acne treatment for back

New concept PDT GEL riboflavin and tryptophan treatment principle

Photosensitizer is very important in PDT photodynamic therapy

1. Riboflavin activates tryptophan after exposure to blue light to form active free radicals.

2. Active radicals react with water molecules to produce ROS

3. ROS has the effect of reducing the secretion of acne bacteria and sebum

4. After the influence of tryptophan, by-products rapidly decompose as amino acids are discharged through metabolic pathways in the skin.

5. It does not cause any side effects, no need to worry about redness, burning or tanning


Why not use chlorophyll ALA aminolevulinic acid component of photosensitizer?

5-Aminolevulinic acid (ALA), an endogenous biochemical substance produced by ALA dehydratase and a series of enzymatic actions to produce protoporphyrin IX (PPIX) with strong photosensitivity. The synthesis speed of PPIX depends on the picking speed of this product, and this product is regulated by the feedback of free hemoglobin concentration. The exogenous product can bypass the feedback inhibition system and make the cells synthesize a sufficient amount of PPIX. The acne containing PPIX is irradiated with 420-640 nm light, and singlet oxygen (-O2) is generated during energy transfer. When the oxygen reaches a certain concentration, cell death (phototoxicity) can be induced.

Side effects: When treated with ALA, there is no selective destruction of normal tissues around it, such as oxidized proteins, liposomes and other subcutaneous cell structures. Oxygen free radicals generated under the pathological conditions of this product overload will lead to Acute periodic porphyria. In addition, this product will cause the release of iron ions in ferritin. Which will aggravate the oxidation of cells, it will lead to acute periodic porphyria. Some people will have erythema and swelling. ALA aminolevulinic acid also causes pigmentation, which is an anti-black phenomenon in some people during the treatment.

Differences between photosensitizers for PDT photodynamic therapy
Differences between photosensitizers for PDT photodynamic therapy


PDT photosensitizer for PDT photodynamic therapy
PDT photosensitizer for PDT photodynamic therapy

Treatment application process

1. Clean and disinfect skin before doing PDT photodynamic therapy

2. Squeeze the acne on your face (use a needle to gently puncture the area of the acne and squeeze out the pus)

3. Remove the cover of PDT Gel and replace it with a closed conical cover

4. Apply PDT Gel to your face, avoiding applying near the lips and around your eyes

5. Cover the face with plastic wrap, leave the lips and eyes area

6. Put the towel on your face for 20 minutes to block the light source to allow the product to fully penetrate. If you operate in a lighted room, you need to turn off the light.

7. Turn on the 415nm, 635nm pulsed LED light, each pulse for 10 minutes

8. Complete treatment, clean the skin

9. Place the Glamour Bio Cellulose Repair Mask for 20 minutes to clam your skin.

10. Always apply sunscreen after treatment, you need to apply sunscreen during the whole treatment period.

PDT photodynamic acne therapy usually takes 3 to 5 sessions for a complete treatment, depending on the skin condition of each patient. Each treatment interval is one week, but can be adjusted according to the patient’s skin condition. You can perform other skin treatment when doing PDT photodynamic therapy.

PDT photodynamic therapy before & after pictures
PDT photodynamic therapy before & after pictures
PDT photodynamic therapy acne treatment review
PDT photodynamic therapy acne treatment review

Important things to know after procedure

1. You can wash your face or having light makeup on the same day after treatment.

2. Please be gently cleaning your face to avoid irritating the skin.

3. Please try to avoid UV rays during the whole PDT photodynamic acne treatment always remember to apply sunscreen.

4. Please do not go to sauna, or having heavry exercise, etc. for 2-3 days after use.

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HyalDew dermal fillers all

希雅德ALL是整个系列中最硬的。 我们的大多数亚洲医生都将它用于垫鼻梁,丰下巴等需要塑形的部位。 当在鼻梁上注射大分子的时候,随着时间慢慢吸收的情况下,希雅德不会像别的品牌的玻尿酸一样鼻梁会变宽,希雅德一直会维持原本直挺的形状。 希雅德可以维持约1到2年。 在各大韩国品牌的玻尿酸当中,希雅德也叫韩国版丝丽,因为硬度够,是唯一一个韩国品牌的玻尿酸有着丝丽一样骨感的效果,但丝丽因含有甘露醇所以不容易被溶解酶所溶解,但海德却可以快速被溶解酶所溶解。


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黄褐斑是一种常见的获得性皮炎,由浅褐色至深褐色的斑点和斑块组成,涉及面部和颈部的阳光照射区域。这种疾病通常在女性中观察到,男性仅代表10%的病例; 然而,这种疾病的临床组织学特征在两性中都是相同的。虽然黄褐斑的确切原因尚不清楚,但遗传易感性,紫外线(紫外线)照射,怀孕,性激素,避孕药,甲状腺疾病,化妆品,光毒药物(如抗癫痫药物)等因素已被确定为一些常见诱发黄褐斑的促成因素。


对于黃褐斑使用不同的治療方式也很难彻底清除,包括使用防曬,色素減退劑和激光療法。 有的疗法甚至使用漂白劑與其他療法一起開處方,如維甲酸,外用皮質類固醇或表面剝離劑,但是这对皮肤伤害大,副作用也大。近來,一些研究人員發現了氨甲環酸(TA)對黃褐斑病變有抑製作用,也可以防止紫外線引起的色素沉著。



黑色素合成的主要成因是作為纖溶酶活性的結果,花生四烯酸(AA)(前列腺素的前體)和α-黑素細胞刺激激素的水平的細胞內釋放增加从而导致黑色素的合成。 因此,氨甲環酸的抗纖溶酶活性化被認為是該藥物对于抑制黑色素合成的主要機制。局部顯微注射氨甲環酸的臨床試驗結果證明成效明显, 在顯微注射氨甲環酸後8週,觀察到患者黃褐斑面積和嚴重程度指數(MASI)評分顯著降低,無明顯副作用。




美乐桃心淡斑精华是韩国BR研究所的VITA C COMPLEX FORMULATION技术特别研发的完美Anti-Melasma疗法, BR Pharm以治疗皮肤处方成分为基础研究开发,主要原料为氨甲环酸,止血环酸,维他命C,烟酰胺,曲酸等有效成分,可以均匀肤色和降低来自光老化的皮肤损害,因为对渴望健康皮肤的患者带来最大的满意度。专门针对黄褐斑,雀斑,晒斑等色素沉着和不均匀肤色而研发的淡斑美白治疗方案,有效抑制黑色素产生,对治疗大部分女性都有的黄褐斑有明显效果。


研究表示,美乐桃心淡斑精华里面的主要成分止血环酸和氨甲环酸是美白针的主要成分,也是治疗黄褐斑最安全而无副作用的有效治疗方案。淡斑效果是为他C的50倍,AHA的10倍。比起美白针通过静脉注射从而作用于患部,美乐桃心独特VITA C COMPLEX技术可使产品通过局部注射,电动微针的方式直接作用于患处,更能有效抑制黄褐斑,雀斑等斑点问题。氨甲環酸(TA)具有增白效果,特別是對於紫外線誘導的色素沉著過度,包括黃褐斑有显著的抑制作用。根据美国国家生物技术信息中心研究显示,氨甲環酸溶液的有效性和安全性,並將其與對苯二酚和地塞米鬆的聯合溶液進行比較,作為女性黃褐斑的黃金標準治療方法。这项研究是一項為期12週的雙盲試驗,在伊朗伊斯法罕進行。 50名伊朗黃褐斑患者在面部的一側施用3%氨甲環酸局部溶液,並且在另一側每天兩次施用3%氫醌+ 0.01%地塞米鬆的局部溶液。在基線時評估黃褐斑面積和嚴重程度指數(MASI)和副作用,並且在皮膚科醫生將要比較的照片之前和之後每4週評估一次。患者滿意度記錄在第12週。研究结果显示,患者和研究者對兩組間黃褐斑改善的滿意度無差異(P <0.05)。 然而,與氨甲環酸相比,對苯二酚+地塞米鬆的副作用顯著(P = 0.01)。 該研究的結果將氨甲環酸局部溶液作為治療黃褐斑的有效且安全的藥物。


美乐桃心淡斑精华的止血环酸成分有助维持透明的皮肤,抑制黑色素的产生,对于黑痣,雀斑和色素沉着有显著的疗效。止血环酸更可以调节皮肤的PH值,调节碱性和弱碱性,有助于维持健康的皮肤。更对受损的皮肤进行调理,给下垂的皮肤赐予弹性,赐予皮肤活力。 维他命C是水溶性产品,普通的维他命C遇到光会急速失效,变色和变质,BR PHARM的独有VITA C COMPLEX技术抑制维他命C氧化,更能有效让产品做出针对性治疗。 美乐桃心淡斑精华抑制把帮助Tyrosine酪氨酸变化为melanin黑色素反应的tyrosinase酪氨酸酶,防止melanin黑色素形成,从而平均减少色素沉着而获得光亮的皮肤。



  • 阻断黑色素细胞生成的传达物质纖溶酶,防止其活性化从而抑制黑色素产生。
  • 防止黑色素细胞内黑色素的生成,抑制络氨酸酶的活动。
  • 对于分布广泛的肝斑更能减少现有黑色素,助于淡化其颜色。
  • 抑制被角质形成细胞诱导的黑色素合成。
  • 促进皮肤内的光感因子,打造自然透明的皮肤




  1. 深层清洁脸部,消毒皮肤
  2. 一次根据使用范围决定使用量,通常脸部为一小瓶。开封铝盖后,可使用针管把产品抽出,直接涂抹于脸部,避开唇部和眼周。
  3. 可使用离子导入仪导入,也可以使用MTS电动微针全脸打圈导入。
  4. 操作完毕后使用LED黄灯照射20分钟。
  5. 敷上感铭纳米生物纤维再生面膜20分钟作镇静管理。
  6. 收尾清洁工作,涂抹术后防晒。


  • 电动微针,微针滚轮
  • 电离子导入
  • 混合水光作水光注射
  • 超声波导入
  • LED光动力疗法


  • 一周一次,建议五次一疗程,可根据患者皮肤状态调整次数
  • 美乐桃心原液2.5ml混合医用蒸馏水或者生理盐水,建议1:1比例混合使用
  • 不混合生理盐水单独操作美乐桃心淡斑针对于敏感皮肤有一定刺激性,建议混合使用



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PDT photodynamic therapy用于光动力治疗的PDT焕肤祛痘疗法

PDT焕肤是一种无副作用的光敏剂,配合使用欧米茄LED光源治疗痤疮,它被称为PDT光动力祛痘疗法。 比起传统ALA成分的光敏剂产品,这是PDT痤疮治疗的新概念,利用皮肤蛋白质组分色氨酸杀死细菌并释放副产物氨基酸。 没有灼伤,没有疼痛,没有晒黑,没有副作用! 现在您可以体验PDT焕肤有效治疗痤疮。除了脸部以外,PDT焕肤也可以用在后背,不需要繁琐的MTS电动微针导入,不需要调和产品消耗大量时间,只需要涂抹上皮肤后配合LED光源就可以治疗。脸部或身体,只要有痤疮部位面积将不再麻烦,治疗更为快捷与方便!




什么是PDT Acne treatment光动力疗法?

光动力疗法(PDT),有时称为光化学疗法,是一种涉及光和光敏剂的光疗法。 PDT已被证明能够杀死微生物细胞,包括细菌,真菌和病毒。 PDT焕肤广泛用于治疗痤疮。 这种治疗特别适用于对其他治疗无反应的严重痤疮病例。 光动力治疗(PDT)对于其他皮肤病症,如晒伤皮肤,癌前期细胞和皮肤感染也有作用。 PDT焕肤光动力疗法还可以减少皮肤上产油腺体的大小和活性,称为皮脂腺。 这些腺体的过度活跃和炎症都会令痤疮更为严重。比起非发炎中的痤疮,PDT焕肤往往对于炎症痤疮更为有效果


5-氨基酮戊酸(ALA),本品是一种内源性的生化物质经ALA脱水酶及一系列酶促作用,生成具有强光敏作用的原卟啉Ⅸ(PPⅨ)。PPⅨ的合成速度取决于本品拾 成速度,而本品又受游离血红蛋白浓度的反馈调节,外源性的本品可绕过反馈抑制系统,使细胞合成聚起足量的PPⅨ。用420~640nm光辐射含有PPⅨ的痤疮,在能量转移过程中产生单态氧(-O2),这种态氧达到一定浓度时可以引发细胞死亡(光毒性)。


新概念PDT GEL核黄素与色氨酸治疗原理

PDT photodynamic therapy中,photosensitizer光敏剂是重要的








  • 杀死皮肤上的致痤疮细菌
  • 操作更为方便简单,无需调和产品无需电动微针
  • 只影响目标细胞,有助于维持皮肤的完整性
  • 减少皮脂腺的大小和活动
  • 帮助淡化老痤疮疤痕
  • 不会造成疤痕
  • 治疗可能与痤疮同时发生的其他皮肤病症,如老年斑和红斑痤疮
  • 如果需要,可以和药物一起使用,但异维A酸(维甲酸)

PDT焕肤光动力疗法的另一个重要好处是它不涉及使用抗生素或口服类维生素A,如维甲酸。 这使PDT焕肤成为不能服用这些药物的人的可行治疗方法。













PDT焕肤光动力祛痘通常3到5次为一个疗程,取决于每个患者的皮肤状态。 每次治疗间隔为一周,但可以根据患者的皮肤状况作调整。 进行PDT焕肤的时候也可以与其他治疗同时进行。



1. 当天可洗脸或者轻度化妆

2. 使用当天晚上请温和清洁脸部避免刺激皮肤

3. 光动力治疗期间请尽量隔离紫外线,做好防晒工作

4. 使用后2-3天内请不要进行桑拿,剧烈运动等让身体发热的活动


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Tranexamic Acid Injection for Melasma Treatment

Injection Melasma Treatment with Tranexamic Acid & other ingridents

melasma treatment

What s Melasma?

Melasma is a common skin problem. It is a common acquired dermatitis of light to dark brown macules and patches involving the sun-exposed areas of the face and neck. Most people get it on their cheeks, bridge of their nose, forehead, chin, and above their upper lip. It also can appear on other parts of the body that get lots of sun, such as the forearms and neck.

The cause of Melasma

It isn’t totally clear what causes melasma. Darker-skinned individuals are more at risk than those with fair skin. Estrogen and progesterone sensitivity are also associated with the condition. Some factors such as genetic susceptibility, ultraviolet (UV) light exposure, pregnancy, sex hormones, contraceptive pills, thyroid disease, cosmetics, phototoxic drugs (e.g., antiseizure medications) have been identified as some common contributing factors in developing melasma. Additionally, sun exposure can cause melasma because ultraviolet rays affect the cells that control pigment (melanocytes).

melasma treatment

What is Tranexamic Acid?

Tranexamic acid is a procoagulant agent that is approved by the US Food and Drug Administration for treatment of menorrhagia and to prevent hemorrhage in patients with hemophilia undergoing tooth extractions. Through its inhibitory effects on the plasminogen activation pathway, tranexamic acid also mitigates the UV radiation–induced pigmentation response. Systemic tranexamic acid has consistently been reported as an effective treatment of melasma.

How does Tranexamic Acid effects melasma?

The intracellular release of arachidonic acid (AA), a precursor of prostanoid, and the level of alpha-melanocyte-stimulating hormone increase as the result of plasmin activity. These two substances can activate melanin synthesis. Therefore, the anti-plasmin activity of tranexamic acid is thought as the main mechanism of hypopigmentory effect of this agent. The result of a clinical trial of localized microinjection of tranexamic acid proved to be promising.  Tranexamic acid exerts effects on pigmentation via its inhibitory effects on UV light–induced plasminogen activator and plasmin activity. UV radiation induces the synthesis of plasminogen activator by keratinocytes, which results in increased conversion of plasminogen to plasmin. Plasminogen activator induces tyrosinase activity, resulting in increased melanin synthesis. The presence of plasmin results in increased production of both arachidonic acid and fibroblast growth factor, which stimulate melanogenesis and neovascularization, respectively. By inhibiting plasminogen activation, tranexamic acid mitigates UV radiation–induced melanogenesis and neovascularization. There is a clinical trial proved that tranexamic acid injections has a promising result for reducing melasma. Significant decrease in the Melasma Area and Severity Index (MASI) score with no significant side effects was seen after 8 weeks of microinjection of tranexamic acid.



What is Melatocin Melasma Treatment?

Melatocin Essence is the perfect Anti-Melasma therapy developed by VITA C COMPLEX FORMULATION technology by BR Research Institute of Korea. The main ingredients of Melatocin Essence are tranexamic acid, hemostatic acid, vitamin C, niacinamide, kojic acid, etc. These formulas can even out skin tone and reduce skin damage from photoaging, provides the greatest satisfaction for patients who are eager for healthy skin.

tranexamic acid anti melasma

Melatocin Essence is specifically desig for the treatment of chloasma, freckles, pigmentation and uneven skin tone. Melatocin Essence can inhibit melanin production effectively, it has a significant effect on the treatment of melasma.

According to the study, the main components of Melatocin Essence, hemostatic acid and tranexamic acid are the most effective treatment for treating chloasma without side effects. The effect of anti-melasma is 50 times  of Vitamin C and 10 times of AHA. The unique VITA C COMPLEX technology can make the ingredients directly act on the affected part through local injection and electric microneedle, which can effectively inhibit the development of dark spots.

melatocin melasma treatment

Melatocin Essence Principle of action

  • Blocks the melanocyte-producing substance plasmin, preventing its activation and inhibiting melanin production.
  • Prevents the production of melanin in melanocytes and inhibits the activity of tyrosinase.
  • It can reduce the existing melanin and help to dilute its color.
  • Inhibition of melanin synthesis induced by keratinocytes.
  • Create natural and transparent skin.

Melatocin Essence process

  • Deep cleansing of the face, disinfecting the skin
  • One vial each treatment on the face. Apply it directly to the face, avoiding the lips and the eye area.
  • It can be apply using an iontophoresis skin care device or apply using a MTS electric microneedle.
  • After the procedure, use the LED yellow light for 20 minutes.
  • Apply Glamour Bio-Cellulose repair mask for 20 minutes for skin clamming.
  • Finish the cleaning work and apply sunscreen after procedure.

Melatocin Essence application method

Electric micro needle, micro needle roller
Electron iontophoresis device
Mixed with skin boosters for mesotherapy
Ultrasonic device
LED photodynamic therapy

Melatocin Essence Dosage

  • Once a week, it is recommended to have five treatments, which can be adjusted according to the patient’s skin condition.
  • Each vial of 2.5ml mix with distilled water or saline, it is recommended to mix 1:1 ratio.


Please apply sunscreen during the treatment period.

Do not go to sauna or excises within 2 days after treatment.

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