U cog PDO thread is linked with two 19G cannula needle at both the end of the spike PDO thread, it is strong enough to pull up sagging skin of the jaw line, especially it could used for none surgical brow lift. This breakthrough product which replaces what was possible only as a major surgery through incision with simple procedure is produced by leading-edge technology of U COG pdo lifting thread. By having two cannulas while pulling from two directions, the strength is strong enough and the lifting effect of the COG thread became much stronger, it could be use for breast lifting, butt lifting, jaw line lifting, forearms around triceps and brow lift. Inserted with its cannula to prevent patient from brushing and swelling.
Unlike similar products, it is made of 48cm thread so that it can be easily applied to any part and it is filled with high quality spikes cutting throughout the thread. The needle is also specially made and does not break or bend. U COG double cannula pdo lifting thread for none surgical brow lift is mainly applied to the forehead, upper part of each eyebrow so that drooped eyelids can be lifted. So with a single treatment, you may have an effect for enlarging the eyes, for spreading the whole wrinkles of the eye tails and making the forehead smooth.
How to perform a none surgical brow lift with U Cog double needles pdo thread
The size of the thread is in 21G 110 mm cannula, the thread is 470mm
SM Strong Topical Anesthetic Numbing Cream Fast Penetration Pain Relief
Topical anesthesia contains lidocaine, which is a medication used to to reduce pain in small areas including the skin, nose, and throat. Injection lidocaine is used to treat ventricular tachycardia and to perform nerve block while topical numbing cream is used to used to numb tissue in a specific area. These products are available as gels, sprays, solutions, creams, and ointments. SM Numbing cream is most commonly used to relieve pain caused by waxing, piercing, tattooing, tattoo removal, micro needling, skin boosters injection and laser treatments as well.
Strongest Topical Anesthetic : SM Numbing Cream
SM numbing cream is made in Korea, and it is approved by the KFDA, with 10.56% lidocaine, it is safe to use, it won’t feel burning or allergies compares to other brands or China made products. 10.56% lidocaine provides ultra strong numbing effect, it is the most strongest topical anesthetic numbing cream without any side effects.
White to yellowish cream, 500G, 17.56oz
Store at room temperature between 1 to 30 degrees centigrade.
3 years from manufacturing date. MADE IN KOREA.
1. Do not apply to the following people:
You or your partner oversensitive to lidocaine and or another amide preparation.
Anyone with external wound or inflammation on the desired area.
Don’t use to a pregnant woman.
2. Extra care needed to the following people, with liver and kidney disease.
3. Warnings of usage:
External use only. Avoid contact with the eyes and nose.
Recommend NOT to use repeatedly on the same area.
Keep out of reach of children
Store at room temperature away from light and moisture. Do not freeze.
Keep this product away from heat and open flames.
For best results, SM Numbing cream should be applied 20 to 30 minutes before the procedure. The anesthetic effect should last about an hour.
SM NUMBING CREAM PRODUCT INSTRUCTION
Lidocaine is volatile ingredient.
Please make sure to close the cover tightly every time after using, otherwise anesthetic effect will be less.
Please follow the instruction to maximize the anesthetic effect.
1. Apply thick amount of the cream on the treatment area.
2. Cover the applied area with the plastic wrap to help absorbing lidocaine into the skin.
3. After 25 to 35 minutes, remove the plastic wrap, clean the cream off with cotton and saline water.
Leave the cream on the skin longer for better result, normally 30 minutes will be enough for micro needling, skin boosters injection, laser treatments. If you are doing tattoo, leave it on for more than 45 minutes.
Don’t remove the plastic wrap until you feel the numbing effect.
Melsmon human placenta injection for anti-aging & skin rejuvenation
Melsmon human placenta injection is known as for correction of climacteric symptoms in premenopausal women. Japan’s Melsmon placenta combines the magical power of nature with modern high-tech development to provide you with the best safe and efficient way for you to improve your physical condition, it also focus on your skin & facial rejuvenation. Placenta in Asia has been a traditional medicine in China for over hundreds of years. China’s ancestors have long had experience using placenta, because it has a variety of hormones that are lacking in menopausal women, it is a nutrient for activating cells. In the past, after the birth of the fetus, the placenta that had been removed, removed micro-vessels and water, dried it, and grind it. It was used as a medicine in China, especially for menopausal women or women. Japan with its high technology developled the eastern medicine and turn them into human placenta injection, a more direct way of absorbing the placenta.
From the inspiration of the Chinese placenta medicine from old ages, Japan is one of the countries with the longest history of placenta research, with the most complete modern placenta technology, Japan became the manufactory of the placenta products in the world. Japan Melsmon human placenta is a product that has approval of the Japanese Ministry of Health, Labour and Welfare, it is manufactured by Melsmon Pharmaceutical Co., Ltd. Japan Melsmon human placenta injection is rich in a variety of amino acids, active peptides, various growth factors and repair factors, through the body circulation to comprehensively regulate the body’s various functions. Through the circulation of the human body, it can comprehensively regulate various functions of the body, enhance beauty, enhance resistance, regulate endocrine, and delay premature aging and aging of the internal organs. Melsmon also revitalizes energy, people usually feel more energetic after treatment. As a top-notch product in Japan, Melsmon human placenta is frequently favored by political and business elites and entertainers. Melsmon human placenta’s famous name has long been a household name in the domestic beauty industry and among Asia.
The function of Melsmon Placenta
To improve the metabolic process for protein and amino acid and also breaking up of glucose to produce energy. In this respect, the placenta plays the role of a liver.
The fetus is unable to respire with the external oxygen directly. Hence it must go through the placenta to exchange the required oxygen with carbon dioxide through the mother’s blood. The function is akin to the lung of a human body.
Excretory Function for Metabolic By-products
The fetus cannot discharge the metabolic by-products by itself. The by-products are channeled to the placenta for processing and this is similar to the function of kidney for an ordinary person.
In order to maintain the normal body function during pregnancy, essential hormones must be produced and made available through secretion. During the initial period, the placenta stimulates the mother’s ovary to produce hairy glands and this enhances the secretion of female hormone. In the final stage of pregnancy, it secrets the hormone for ovulation automatically and this is akin to the function of the pituitary gland and the ovary.
The fetus does not possess any immunity against diseases. Therefore, it has to acquire the antibody from the mother’s body through placenta.
The numerous functions of placenta are beyond the scope of modern medical science. If an organ akin to placenta could be manufactured by artificial means, it will certainly become a great discovery for the world. Unfortunately modern medical science is still unable to do this but more research is being done.
Main ingredients of Melsmon
1. Nucleic acid:
Nucleic acid is the basic substance in the nucleus of human body. It plays an important role in the growth and proliferation of cells, especially the normal metabolism of skin tissue, the promotion of skin cell viability and the repair of damaged cells. It determines the aging process of cells.
2. Amino acids:
Contains more than 30 kinds of amino acids, including 8 essential amino acids such as cystine, cysteine, leucine, arginine, serine and jiric acid. Amino acids are the basic substances that make up proteins in human cells. Therefore, it is the basic unit of tissue repair, the constituent components of enzymes and hormones, and some of the energy is also derived from them. It plays an important role in the growth and development of adolescents and the health and longevity of middle-aged and elderly people.
3. Natural placental immune protein
Placental tissue fluid is rich in HGG (chorionic gonadotropin), TSH (thyrotropin), prolactin, steroid hormone and antibody protein, especially for women with severe skin aging. It can improve sexual function, delay the thinning of vaginal mucosa and the relaxation of perineal sphincter. It also heals endocrine disorders caused by menopausal syndrome and irregular menstruation, it improves skin wrinkles, pigment spots and so on. Antibody proteins can improve the body’s resistance to infectious diseases, especially respiratory and digestive diseases.
4. Cell growth factor population
Human placenta is rich in epidermal growth factor (EGF), basic velvet cell growth factor (BFGF), platelet cell growth factor (PDGF), transforming growth factor (TGF), islet cell growth factor (IGF) and Cell growth promoting factor. All of these factors promote the production and division of the corresponding cells. Skin cells, fibroblasts, vascular endothelial cells, smooth muscle cells, etc. are activated and grown. TGF also activates fibroblasts, inhibits the keratinocytes at the outermost layer of the epidermis, and synergizes with the cell growth factor group to significantly improve the skin, improve skin metabolism, and maintain skin radiance.
5. Multi-type collagen and nutrients
This product is rich in multi-type collagen, the skin ageing with the increase of age, the collagen component in the skin dermis is degenerated, the collagen component is reduced, the skin’s toughness and elasticity are reduced. Once when the collagen component is supplement, it will restore the elasticity and toughness of the skin.
One treatment contains 50 vials, 1 vial for each injection. Melsmon is apply through subcutaneous injection, and inject 1 vial every two days for the first month, and inject twice a week for the rest.
Mix 1 vial of Melsmon with skin booster to inject on the face with Ice shot injector.
Liporase Hyaluronidase : dissolve hyaluronic acid dermal fillers that went wrong
Liporase Hyaluronidase is made in Korea and it is approve by KFDA. Hyaluronidase is used to dissolve hyaluronic acid fillers that have been placed incorrectly, excessively, or unevenly. It is injected into the same locations that the filler already is. Hyaluronidase is also used in emergency situations where dermal filler has been inadvertently injected into an artery causing occlusion of the blood supply. It is injected into the vicinity of the dermal filler that needs to be dissolved.
What is hyaluronidase?
Hyaluronidase is an enzyme (compounded by special pharmacies) that causes hydrolysis (breakdown) of hyaluronic acid. It is often referred to as a reversal agent for hyaluronic acid fillers. When the enzyme is injected it dissolves the synthetic hyaluronic acid filler, leaving your own intact. Liporase Hyaluronidase is made in Korea. It is used to dissolve hyaluronic acid based dermal fillers that have been placed incorrectly, excessively, or unevenly. Hyaluronidase is also used in emergency situations where dermal filler has been inadvertently injected into an artery causing occlusion of the blood supply. It is injected into the vicinity of the dermal filler that needs to be dissolved.
1 box : 10 vials
Each vial contains 1,500 I.U. of hyaluronidase to be mix with 3cc of saline.
Uses of Hyaluronidase Injection:
To remove filler, hyaluronidase can be injected to dissolve the hyaluronic acid in dermal fillers.
To increase the effect of lipodissoving injection, hyaluronidase can be added to the cocktails of fat melting injection.
Hyaluronidase is often combined with local anaesthetic to increase the diffusion of local anaesthetic.
Process of Hyaluronidase Injection for filler dissolving:
Mix 3cc of saline to 1 vial of Hyaluronidase, it could disslove 3cc of hyaluronic acid.
Hyaluronidase is injected, along with lidocaine (and sometimes epinephrine), into the area where the filler needs to be dissolved.
Hyaluronic acid filler will start to be dissolve right away, and it will be absorb by the body in a few hours.
Process of adding Hyaluronidase to lipodissolving injection:
Mix 5cc of saline to 1 vial of Hyaluronidase, it could be add to a 10cc lipodissolving Vline injection. If it is 30cc, add 2 vials of Hyaluronidase.
Hyaluronidase is mixed with Vline injection, it is injected along with lidocaine into the fat layer evenly.
Massage the area where it was treated for 15 minutes each day and 7 days in a roll, apply hot packing after massage.
There have been a few reports that some people may have an allergy to hyaluronidase, which happens to those who are allergic to bee stings.
Hyaldew dermal fillers : Korean long lasting cosmetic fillers with patented micro beads technology
Hyaldew dermal fillers are manufactured in Korea and is the only Korean hyaluronic acid with CE certified. Hyaldew is also KFDA and GMP certified by Korea, guaranteeing safety and quality. Hyaldew’s unique patented micro-bead cross linking technology is arguably the most influential brand of dermal fillers in Korea. It is exported worldwide to the United States, Europe, China, South America and the Middle East. Hyaldew dermal fillers are the leading product of Korean hyaluronic acid dermal fillers in the world. Hyaldew dermal fillers use 100% hyaluronic acid, without any other additions, using HA multi-stage micro-bead cross linking technology to achieve ultra long lasting result! Hyaldew is made by Bioplus Korea, other famous products of Bioplus such as Glamour skin boosters, Dene B body fillers, and many more!
For dermal fillers itself, cross linking technology is the most important step in the history of hyaluronic acid development. Hyaluronic acid with cross linked last much longer. Hyaluronic acid without cross linked is a joint lubricant, such as Hyaron, which is used as skin boosters in China.
Hyaldew dermal fillers patented microbead cross linking technology is another major technological breakthrough in the natural cross linking technology of hyaluronic acid. So what is the difference between artificial cross linking and natural cross linking technology?
In contrast, the artificial cross linking technology has more impurities. Fillers with natural cross linking techonology can be totally absorbed by the body, and nothing remains. It will absorb and decompose with the metabolism of the human body, it doesn’t cause any harm to the body. But fillers with artificial cross linking technology usually cause a lot of remains the body.
Hyaldew dermal fillers, while maintaining the most natural hinges, guarantees the durability of hyaluronic acid with advanced and stable patented bead hinge technology, which not only maintains the 100% natural characteristics of hyaluronic acid, but also solves the short hyaluronic acid maintenance time in the absorption process. The disadvantage of deformation.
Hyaldew dermal fillers has completed an export license at Seoul National University Hospital and passed the strict 5-year clinical trial in Japan, making it the safest and most effective hyaluronic acid product.
Patent cross linking technology introduction:
1. Hyaldew’s three-stage decomposition and combination process:
2. Multi-stage cross linking technology Semi-solid gel morphology, which lasts longer.
3. Advantages of our patent: Breaking through the limitations of traditional cross linking technology, and eliminating the short maintenance time of fillers and unsatisfactory plasticity.
Hyaldew ALL: Suitable for nose & chin augmentation, deep filling (macromolecule) 1 ml x1
The Hyaldew is the hardest in the whole Hyaldew series. Most of our Asian doctors use it for nose & chin augmentation. When injecting Hyaldew All on the bridge of the nose, Hyaldew will not widen the bridge of the nose like other brands of hyaluronic acid, and Hyaldew All will maintain the original straight shape. Hyaldew All can last for about 1 to 2 years. Among the major Korean brands of hyaluronic acid, Hyaldew All is also called the Korean version of Vivacy Stylage XXL, because the hardness of the filler itself, it is the only Korean brand of hyaluronic acid that shapes Asian nose bridge like Stylage XXL, but Stylage XXL is not easy to be melt by Hyaluronidase because of the mannitol component. Hyaldew can be quickly dissolved by the Hyaluronidase.
Hyaldew MID: Suitable for nasolabial fold, temples, forehead, cheeks, deep wrinkles, etc. (medium molecule) 1 ml x1
Hyaldew FINE: Suitable for lips, fine lines, under eye areas etc. (small molecule) 1 ml x1
PDT photodynamic acne therapy by using a non-side-effect photosensitizer that works with Omega LED light source to treat acne. It is called PDT photodynamic therapy. PDT GEL is a new concept of PDT acne treatment compared to traditional ALA-based photosensitizers, which use the skin protein component tryptophan to kill bacteria and release by-product amino acids. No burns, no pain, no tanning, no side effects! Now you can experience PDT photodynamic therapy for effective treatment of acne. In addition to the face, PDT gel can also be used on the back or anywhere on your body. Without the need for cumbersome application with MTS electric micro-needle, you don’t need to reconcile the product to consume a lot of time. All you have to do is to apply PDT gel on the skin of the patient along with the Omega LED light source. You can treat your patient’s face or body, as long as there is acne problem. The treatment time is faster and more convenient!
Photodynamic therapy (PDT), sometimes called photochemotherapy, is a light therapy involving light and photosensitizers. PDT has been proven to kill microbial cells, including bacteria, fungi and viruses. PDT skin is widely used to treat acne problems. This treatment is especially useful in cases of severe acne that do not respond to other treatments. PDT acne treatment also has effects on other skin conditions such as sunburned skin, precancerous cells and skin infections. PDT Photodynamic Therapy also reduces the size and activity of oil-producing glands on the skin, called the sebaceous glands. Excessive activity and inflammation of these glands can cause more severe acne. PDT photodynamic therapy is often more effective for inflammatory acne than non-inflammatory acne.
What is PDT photodynamic therapy acne treatment?
New concept PDT GEL riboflavin and tryptophan treatment principle
Photosensitizer is very important in PDT photodynamic therapy
1. Riboflavin activates tryptophan after exposure to blue light to form active free radicals.
2. Active radicals react with water molecules to produce ROS
3. ROS has the effect of reducing the secretion of acne bacteria and sebum
4. After the influence of tryptophan, by-products rapidly decompose as amino acids are discharged through metabolic pathways in the skin.
5. It does not cause any side effects, no need to worry about redness, burning or tanning
Why not use chlorophyll ALA aminolevulinic acid component of photosensitizer?
5-Aminolevulinic acid (ALA), an endogenous biochemical substance produced by ALA dehydratase and a series of enzymatic actions to produce protoporphyrin IX (PPIX) with strong photosensitivity. The synthesis speed of PPIX depends on the picking speed of this product, and this product is regulated by the feedback of free hemoglobin concentration. The exogenous product can bypass the feedback inhibition system and make the cells synthesize a sufficient amount of PPIX. The acne containing PPIX is irradiated with 420-640 nm light, and singlet oxygen (-O2) is generated during energy transfer. When the oxygen reaches a certain concentration, cell death (phototoxicity) can be induced.
Side effects: When treated with ALA, there is no selective destruction of normal tissues around it, such as oxidized proteins, liposomes and other subcutaneous cell structures. Oxygen free radicals generated under the pathological conditions of this product overload will lead to Acute periodic porphyria. In addition, this product will cause the release of iron ions in ferritin. Which will aggravate the oxidation of cells, it will lead to acute periodic porphyria. Some people will have erythema and swelling. ALA aminolevulinic acid also causes pigmentation, which is an anti-black phenomenon in some people during the treatment.
Treatment application process
1. Clean and disinfect skin before doing PDT photodynamic therapy
2. Squeeze the acne on your face (use a needle to gently puncture the area of the acne and squeeze out the pus)
3. Remove the cover of PDT Gel and replace it with a closed conical cover
4. Apply PDT Gel to your face, avoiding applying near the lips and around your eyes
5. Cover the face with plastic wrap, leave the lips and eyes area
6. Put the towel on your face for 20 minutes to block the light source to allow the product to fully penetrate. If you operate in a lighted room, you need to turn off the light.
7. Turn on the 415nm, 635nm pulsed LED light, each pulse for 10 minutes
10. Always apply sunscreen after treatment, you need to apply sunscreen during the whole treatment period.
PDT photodynamic acne therapy usually takes 3 to 5 sessions for a complete treatment, depending on the skin condition of each patient. Each treatment interval is one week, but can be adjusted according to the patient’s skin condition. You can perform other skin treatment when doing PDT photodynamic therapy.
Important things to know after procedure
1. You can wash your face or having light makeup on the same day after treatment.
2. Please be gently cleaning your face to avoid irritating the skin.
3. Please try to avoid UV rays during the whole PDT photodynamic acne treatment always remember to apply sunscreen.
4. Please do not go to sauna, or having heavry exercise, etc. for 2-3 days after use.
Melasma is a common skin problem. It is a common acquired dermatitis of light to dark brown macules and patches involving the sun-exposed areas of the face and neck. Most people get it on their cheeks, bridge of their nose, forehead, chin, and above their upper lip. It also can appear on other parts of the body that get lots of sun, such as the forearms and neck.
The cause of Melasma
It isn’t totally clear what causes melasma. Darker-skinned individuals are more at risk than those with fair skin. Estrogen and progesterone sensitivity are also associated with the condition. Some factors such as genetic susceptibility, ultraviolet (UV) light exposure, pregnancy, sex hormones, contraceptive pills, thyroid disease, cosmetics, phototoxic drugs (e.g., antiseizure medications) have been identified as some common contributing factors in developing melasma. Additionally, sun exposure can cause melasma because ultraviolet rays affect the cells that control pigment (melanocytes).
Tranexamic acid is a procoagulant agent that is approved by the US Food and Drug Administration for treatment of menorrhagia and to prevent hemorrhage in patients with hemophilia undergoing tooth extractions. Through its inhibitory effects on the plasminogen activation pathway, tranexamic acid also mitigates the UV radiation–induced pigmentation response. Systemic tranexamic acid has consistently been reported as an effective treatment of melasma.
How does Tranexamic Acid effects melasma?
The intracellular release of arachidonic acid (AA), a precursor of prostanoid, and the level of alpha-melanocyte-stimulating hormone increase as the result of plasmin activity. These two substances can activate melanin synthesis. Therefore, the anti-plasmin activity of tranexamic acid is thought as the main mechanism of hypopigmentory effect of this agent. The result of a clinical trial of localized microinjection of tranexamic acid proved to be promising. Tranexamic acid exerts effects on pigmentation via its inhibitory effects on UV light–induced plasminogen activator and plasmin activity. UV radiation induces the synthesis of plasminogen activator by keratinocytes, which results in increased conversion of plasminogen to plasmin. Plasminogen activator induces tyrosinase activity, resulting in increased melanin synthesis. The presence of plasmin results in increased production of both arachidonic acid and fibroblast growth factor, which stimulate melanogenesis and neovascularization, respectively. By inhibiting plasminogen activation, tranexamic acid mitigates UV radiation–induced melanogenesis and neovascularization. There is a clinical trial proved that tranexamic acid injections has a promising result for reducing melasma. Significant decrease in the Melasma Area and Severity Index (MASI) score with no significant side effects was seen after 8 weeks of microinjection of tranexamic acid.
What is Melatocin Melasma Treatment?
Melatocin Essence is the perfect Anti-Melasma therapy developed by VITA C COMPLEX FORMULATION technology by BR Research Institute of Korea. The main ingredients of Melatocin Essence are tranexamic acid, hemostatic acid, vitamin C, niacinamide, kojic acid, etc. These formulas can even out skin tone and reduce skin damage from photoaging, provides the greatest satisfaction for patients who are eager for healthy skin.
Melatocin Essence is specifically desig for the treatment of chloasma, freckles, pigmentation and uneven skin tone. Melatocin Essence can inhibit melanin production effectively, it has a significant effect on the treatment of melasma.
According to the study, the main components of Melatocin Essence, hemostatic acid and tranexamic acid are the most effective treatment for treating chloasma without side effects. The effect of anti-melasma is 50 times of Vitamin C and 10 times of AHA. The unique VITA C COMPLEX technology can make the ingredients directly act on the affected part through local injection and electric microneedle, which can effectively inhibit the development of dark spots.
Melatocin Essence Principle of action
Blocks the melanocyte-producing substance plasmin, preventing its activation and inhibiting melanin production.
Prevents the production of melanin in melanocytes and inhibits the activity of tyrosinase.
It can reduce the existing melanin and help to dilute its color.
Inhibition of melanin synthesis induced by keratinocytes.